State of the Art: Degenerative Mitral Valve Disease

Joanna Chikwe, David H. Adams

Research output: Contribution to journalReview articlepeer-review

22 Scopus citations


Mitral valve repair offers superior long-term survival, freedom from cardiac morbidity, and quality of life in patients with severe mitral regurgitation compared to medical management and mitral valve replacement; it is the treatment of choice in these patients. Mitral valve repair is the only treatment that restores normal life expectancy to otherwise healthy patients with advanced degenerative mitral valve disease. This review focuses on indications, timing and techniques for mitral valve repair in degenerative disease, emphasising the importance of anatomy in surgical outcomes.

Original languageEnglish
Pages (from-to)319-329
Number of pages11
JournalHeart Lung and Circulation
Issue number5
StatePublished - Oct 2009


  • Barlows disease
  • Degenerative mitral valve disease
  • Fibroelastic deficiency
  • Mitral valve repair
  • Repairability


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