Split dosing of bowel preparations for colonoscopy: An analysis of its efficacy, safety, and tolerability

Lawrence B. Cohen

doi:10.1016/j.gie.2010.04.001

Split dosing of bowel preparations for colonoscopy: An analysis of its efficacy, safety, and tolerability

Lawrence B. Cohen

Research output: Contribution to journal › Review article › peer-review

77 Scopus citations

Abstract

The PM/AM split-dosing regimen has proven to be more effective than the standard 1-day bowel preparation for achieving optimal cleansing of the colon before a colonoscopy. An interval of 6 to 8 hours or less between the second dose of laxative and the time of the colonoscopy appears to be desirable for optimal bowel cleansing, especially within the ascending colon. The split-dose regimen is well tolerated by most patients provided that they understand the rationale for this practice. By improving the quality of bowel preparation and the detection of neoplastic colon lesions, a PM/AM split-dose regimen can be expected to increase the overall efficiency and effectiveness of colonoscopy and CRC screening.

Original language	English
Pages (from-to)	406-412
Number of pages	7
Journal	Gastrointestinal Endoscopy
Volume	72
Issue number	2
DOIs	https://doi.org/10.1016/j.gie.2010.04.001
State	Published - Aug 2010
Externally published	Yes

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abstract = "The PM/AM split-dosing regimen has proven to be more effective than the standard 1-day bowel preparation for achieving optimal cleansing of the colon before a colonoscopy. An interval of 6 to 8 hours or less between the second dose of laxative and the time of the colonoscopy appears to be desirable for optimal bowel cleansing, especially within the ascending colon. The split-dose regimen is well tolerated by most patients provided that they understand the rationale for this practice. By improving the quality of bowel preparation and the detection of neoplastic colon lesions, a PM/AM split-dose regimen can be expected to increase the overall efficiency and effectiveness of colonoscopy and CRC screening.",

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AB - The PM/AM split-dosing regimen has proven to be more effective than the standard 1-day bowel preparation for achieving optimal cleansing of the colon before a colonoscopy. An interval of 6 to 8 hours or less between the second dose of laxative and the time of the colonoscopy appears to be desirable for optimal bowel cleansing, especially within the ascending colon. The split-dose regimen is well tolerated by most patients provided that they understand the rationale for this practice. By improving the quality of bowel preparation and the detection of neoplastic colon lesions, a PM/AM split-dose regimen can be expected to increase the overall efficiency and effectiveness of colonoscopy and CRC screening.

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DO - 10.1016/j.gie.2010.04.001

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JF - Gastrointestinal Endoscopy

IS - 2

ER -

Split dosing of bowel preparations for colonoscopy: An analysis of its efficacy, safety, and tolerability

Abstract

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