TY - JOUR
T1 - Splenic rupture in a newborn with severe hemophilia-case report and review
AU - Tengsupakul, Supatida
AU - Sedrak, Aziza
AU - Freed, Jennifer
AU - Martinez-Carde, Lynda
AU - Fireman, Fernando
AU - Pierre, Louisdon
AU - Sadanandan, Swayam
PY - 2010/5
Y1 - 2010/5
N2 - Summary: Life-threatening splenic rupture is rare in neonates with severe hemophilia. There are only 3 cases of splenic rupture in neonates with hemophilia reported in the literature. We present the case of an infant, born to a hemophilia A carrier mother. The infant was asymptomatic until discharge at 48 hours of age, but presented on the third day of life with shock, abdominal distension, and severe anemia. Computed tomography of the abdomen confirmed the diagnosis of splenic rupture with hemoperitoneum. The infant recovered after extensive supportive care surgery and factor replacement.
AB - Summary: Life-threatening splenic rupture is rare in neonates with severe hemophilia. There are only 3 cases of splenic rupture in neonates with hemophilia reported in the literature. We present the case of an infant, born to a hemophilia A carrier mother. The infant was asymptomatic until discharge at 48 hours of age, but presented on the third day of life with shock, abdominal distension, and severe anemia. Computed tomography of the abdomen confirmed the diagnosis of splenic rupture with hemoperitoneum. The infant recovered after extensive supportive care surgery and factor replacement.
KW - Hemophilia
KW - Hemophilia carrier mother
KW - Neonate
KW - Splenectomy
KW - Splenic injury
KW - Splenic rupture
UR - http://www.scopus.com/inward/record.url?scp=77952788858&partnerID=8YFLogxK
U2 - 10.1097/MPH.0b013e3181d640ae
DO - 10.1097/MPH.0b013e3181d640ae
M3 - Article
C2 - 20404752
AN - SCOPUS:77952788858
SN - 1077-4114
VL - 32
SP - 323
EP - 326
JO - Journal of Pediatric Hematology/Oncology
JF - Journal of Pediatric Hematology/Oncology
IS - 4
ER -