A microsphere-fiber probe used for spectroscopic analysis of material samples is presented. The monolithic structure is formed by melting the end of a section of optical fiber forming a bead at the distal end of the fiber. Light guided through the fiber and emerges from the sphere focusing to a point beyond the surface. Raman scattering is used to demonstrate the efficacy of the probe, which operates in a bidirectional manner efficiently collecting the scattered light, re-imaging it back into the waveguide, and transmitting it to a spectrometer for dispersion. The probe demonstrates an order of magnitude improvement over the spatial resolution conventional fiber probes. This improvement in spatial resolution and corresponding collection efficiency will aid in critical analyses such as cancer margin detection and material characterization.