Specificity of smooth pursuit eye movement and visual fixation abnormalities in schizophrenia. Comparison to mania and normal controls

Xavier F. Amador; Harold A. Sackeim; Sukdeb Mukherjee; Ronnie Halperin; Priscilla Neeley; Edward Maclin; David Schnur

doi:10.1016/0920-9964(91)90040-X

Specificity of smooth pursuit eye movement and visual fixation abnormalities in schizophrenia. Comparison to mania and normal controls

Xavier F. Amador, Harold A. Sackeim, Sukdeb Mukherjee, Ronnie Halperin, Priscilla Neeley, Edward Maclin, David Schnur

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

Smooth pursuit eye movements (SPEM) were assessed in 30 schizophrenic patients, 12 lithium-free manic patients, and 20 normal controls. Compared to schizophrenic patients, manic patients evidenced less SPEM impairment in an attention enhancing, sinusoidal target motion condition and had superior performance during a visual fixation condition. SPEM and visual fixation dysfunctions may be more common in schizophrenic than in acutely manic patients, even when the latter are characterized by marked attentional dysfunction, poor interepisode psychosocial functioning, and psychosis.

Original language	English
Pages (from-to)	135-144
Number of pages	10
Journal	Schizophrenia Research
Volume	5
Issue number	2
DOIs	https://doi.org/10.1016/0920-9964(91)90040-X
State	Published - Sep 1991
Externally published	Yes

Keywords

(Schizophrenia)
Mania
Smooth pursuit eye movement

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10.1016/0920-9964(91)90040-X

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title = "Specificity of smooth pursuit eye movement and visual fixation abnormalities in schizophrenia. Comparison to mania and normal controls",

abstract = "Smooth pursuit eye movements (SPEM) were assessed in 30 schizophrenic patients, 12 lithium-free manic patients, and 20 normal controls. Compared to schizophrenic patients, manic patients evidenced less SPEM impairment in an attention enhancing, sinusoidal target motion condition and had superior performance during a visual fixation condition. SPEM and visual fixation dysfunctions may be more common in schizophrenic than in acutely manic patients, even when the latter are characterized by marked attentional dysfunction, poor interepisode psychosocial functioning, and psychosis.",

keywords = "(Schizophrenia), Mania, Smooth pursuit eye movement",

author = "Amador, {Xavier F.} and Sackeim, {Harold A.} and Sukdeb Mukherjee and Ronnie Halperin and Priscilla Neeley and Edward Maclin and David Schnur",

note = "Funding Information: Correspondence to: X.F. Amador, Department of Clinical Psychobiology, Schizophrenia Research Unit, Box 2, New York State Psychiatric Institute, 722 West 168th Street, New York, NY 10032, U.S.A. (Tel.: 212-960-2352). *Supported in part by grants from the Mental Illness Foundation, the Van Ameringen Foundation, a Basic Research Support Grant, NIH Grant RR05650, and a NARSAD Young Investigator Award.",

year = "1991",

month = sep,

doi = "10.1016/0920-9964(91)90040-X",

language = "English",

volume = "5",

pages = "135--144",

journal = "Schizophrenia Research",

issn = "0920-9964",

publisher = "Elsevier B.V.",

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TY - JOUR

T1 - Specificity of smooth pursuit eye movement and visual fixation abnormalities in schizophrenia. Comparison to mania and normal controls

AU - Amador, Xavier F.

AU - Sackeim, Harold A.

AU - Mukherjee, Sukdeb

AU - Halperin, Ronnie

AU - Neeley, Priscilla

AU - Maclin, Edward

AU - Schnur, David

N1 - Funding Information: Correspondence to: X.F. Amador, Department of Clinical Psychobiology, Schizophrenia Research Unit, Box 2, New York State Psychiatric Institute, 722 West 168th Street, New York, NY 10032, U.S.A. (Tel.: 212-960-2352). *Supported in part by grants from the Mental Illness Foundation, the Van Ameringen Foundation, a Basic Research Support Grant, NIH Grant RR05650, and a NARSAD Young Investigator Award.

PY - 1991/9

Y1 - 1991/9

N2 - Smooth pursuit eye movements (SPEM) were assessed in 30 schizophrenic patients, 12 lithium-free manic patients, and 20 normal controls. Compared to schizophrenic patients, manic patients evidenced less SPEM impairment in an attention enhancing, sinusoidal target motion condition and had superior performance during a visual fixation condition. SPEM and visual fixation dysfunctions may be more common in schizophrenic than in acutely manic patients, even when the latter are characterized by marked attentional dysfunction, poor interepisode psychosocial functioning, and psychosis.

AB - Smooth pursuit eye movements (SPEM) were assessed in 30 schizophrenic patients, 12 lithium-free manic patients, and 20 normal controls. Compared to schizophrenic patients, manic patients evidenced less SPEM impairment in an attention enhancing, sinusoidal target motion condition and had superior performance during a visual fixation condition. SPEM and visual fixation dysfunctions may be more common in schizophrenic than in acutely manic patients, even when the latter are characterized by marked attentional dysfunction, poor interepisode psychosocial functioning, and psychosis.

KW - (Schizophrenia)

KW - Mania

KW - Smooth pursuit eye movement

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U2 - 10.1016/0920-9964(91)90040-X

DO - 10.1016/0920-9964(91)90040-X

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EP - 144

JO - Schizophrenia Research

JF - Schizophrenia Research

IS - 2

ER -

Specificity of smooth pursuit eye movement and visual fixation abnormalities in schizophrenia. Comparison to mania and normal controls

Abstract

Keywords

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