TY - JOUR
T1 - Soft-tissue Sarcoma of the Hand
T2 - Patient Characteristics, Treatment, and Oncologic Outcomes
AU - Lans, Jonathan
AU - Yue, Kai Lou C.
AU - Castelein, René M.
AU - Suster, David I.
AU - Nielsen, G. Petur
AU - Chen, Neal C.
AU - Calderon, Santiago A.Lozano
N1 - Publisher Copyright:
© American Academy of Orthopaedic Surgeons.
PY - 2021/3/15
Y1 - 2021/3/15
N2 - Introduction:The aim of this study was to describe patient characteristics, treatment, and oncologic outcomes of soft-tissue sarcomas (STSs) of the hand.Methods:Sixty-nine STSs of the hand in adult patients treated at a tertiary referral center were retrospectively included. We describe patient and tumor characteristics along with oncologic outcomes.Results:Epithelioid sarcoma (23%) was the most common histologic subtype, followed by synovial sarcoma (15%). Of all tumors, 17 (25%) were grade I, 22 (32%) were grade II, and 30 (44%) were grade III. The 5-year disease-free survival for epithelioid sarcomas was 75% with a disease survival of 100%, along with a metastatic rate of 15%. Of the patients with a synovial sarcoma, 40% developed metastases, and the 5-year disease-free survival was 68% and the 5-year disease survival was 73%.Conclusion:Hand STSs are aggressive tumors with a high metastatic potential. Even with adequate oncologic treatment, long-term clinical follow-up (10 years) in these tumors is advised. The treating surgical oncologist should not be deceived by their smaller size.
AB - Introduction:The aim of this study was to describe patient characteristics, treatment, and oncologic outcomes of soft-tissue sarcomas (STSs) of the hand.Methods:Sixty-nine STSs of the hand in adult patients treated at a tertiary referral center were retrospectively included. We describe patient and tumor characteristics along with oncologic outcomes.Results:Epithelioid sarcoma (23%) was the most common histologic subtype, followed by synovial sarcoma (15%). Of all tumors, 17 (25%) were grade I, 22 (32%) were grade II, and 30 (44%) were grade III. The 5-year disease-free survival for epithelioid sarcomas was 75% with a disease survival of 100%, along with a metastatic rate of 15%. Of the patients with a synovial sarcoma, 40% developed metastases, and the 5-year disease-free survival was 68% and the 5-year disease survival was 73%.Conclusion:Hand STSs are aggressive tumors with a high metastatic potential. Even with adequate oncologic treatment, long-term clinical follow-up (10 years) in these tumors is advised. The treating surgical oncologist should not be deceived by their smaller size.
UR - http://www.scopus.com/inward/record.url?scp=85102657441&partnerID=8YFLogxK
U2 - 10.5435/JAAOS-D-20-00434
DO - 10.5435/JAAOS-D-20-00434
M3 - Article
C2 - 32932303
AN - SCOPUS:85102657441
SN - 1067-151X
VL - 29
SP - E297-E307
JO - The Journal of the American Academy of Orthopaedic Surgeons
JF - The Journal of the American Academy of Orthopaedic Surgeons
IS - 6
ER -