Small Molecules with Big Promises for Curing Demyelinating Diseases

Fangbin Han; Ming Ming Zhou

doi:10.1016/j.chembiol.2019.04.006

Small Molecules with Big Promises for Curing Demyelinating Diseases

Fangbin Han, Ming Ming Zhou

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

Myelin regeneration by myelinating oligodendrocytes is key to neuronal damage repair for treatment of neurological disorders such as multiple sclerosis. In this issue of Cell Chemical Biology, Allimuthu et al. (2019) report new small molecule inhibitors of cholesterol biosynthesis enzymes that enhance oligodendrocyte formation and subsequent remyelination.

Original language	English
Pages (from-to)	468-470
Number of pages	3
Journal	Cell Chemical Biology
Volume	26
Issue number	4
DOIs	https://doi.org/10.1016/j.chembiol.2019.04.006
State	Published - 18 Apr 2019

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@article{cffdc1db0cd44f2a910112424b822e47,

title = "Small Molecules with Big Promises for Curing Demyelinating Diseases",

abstract = "Myelin regeneration by myelinating oligodendrocytes is key to neuronal damage repair for treatment of neurological disorders such as multiple sclerosis. In this issue of Cell Chemical Biology, Allimuthu et al. (2019) report new small molecule inhibitors of cholesterol biosynthesis enzymes that enhance oligodendrocyte formation and subsequent remyelination.",

author = "Fangbin Han and Zhou, {Ming Ming}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

month = apr,

day = "18",

doi = "10.1016/j.chembiol.2019.04.006",

language = "English",

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T1 - Small Molecules with Big Promises for Curing Demyelinating Diseases

AU - Han, Fangbin

AU - Zhou, Ming Ming

PY - 2019/4/18

Y1 - 2019/4/18

N2 - Myelin regeneration by myelinating oligodendrocytes is key to neuronal damage repair for treatment of neurological disorders such as multiple sclerosis. In this issue of Cell Chemical Biology, Allimuthu et al. (2019) report new small molecule inhibitors of cholesterol biosynthesis enzymes that enhance oligodendrocyte formation and subsequent remyelination.

AB - Myelin regeneration by myelinating oligodendrocytes is key to neuronal damage repair for treatment of neurological disorders such as multiple sclerosis. In this issue of Cell Chemical Biology, Allimuthu et al. (2019) report new small molecule inhibitors of cholesterol biosynthesis enzymes that enhance oligodendrocyte formation and subsequent remyelination.

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U2 - 10.1016/j.chembiol.2019.04.006

DO - 10.1016/j.chembiol.2019.04.006

M3 - Short survey

C2 - 31002801

AN - SCOPUS:85063946823

SN - 2451-9448

VL - 26

SP - 468

EP - 470

JO - Cell Chemical Biology

JF - Cell Chemical Biology

IS - 4

ER -

Small Molecules with Big Promises for Curing Demyelinating Diseases

Abstract

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