Skeletal muscle ventricles as a potential right heart assist or substitute

W. A. Anderson, J. S. Andersen, C. R. Bridges, R. L. Hammond, F. Dimeo, E. E. Frisch, S. Salmons, L. W. Stephenson

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Skeletal muscle ventricles (SMV) were constructed from canine latissimus dorsi muscle and chronically stimulated to pump fluid within a totally implantable mock circulation device. They were stimulated to contract at either 95/min (N = 7) or 54/min (N = 4). The preload was chronically maintained at 20 mmHg. After 1 month of continuous pumping the SMV were capable of generating a stroke work of 0.134x106 ergs and power output of 0.021 watts, representing 61% and 42% of the stroke work and power output of the native canine right ventricle, respectively.

Original languageEnglish
Pages (from-to)241-246
Number of pages6
JournalASAIO Transactions
Volume34
Issue number3
StatePublished - 1988
Externally publishedYes

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