Single mitotic center for rodent cochlear duct

William F. Marovitz, Joel M.A. Shugar

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The pattern of terminal mitosis in mouse otocyst observed by Ruben led him to postulate the existence of a growth zone at the junction of saccular and cochlear primordia. With the use of colchicine, an antimitotic drug, a localized zone of mitotic activity has been demonstrated at this predicted site.

Original languageEnglish
Pages (from-to)225-233
Number of pages9
JournalAnnals of Otology, Rhinology and Laryngology
Issue number2
StatePublished - Mar 1976


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