SIN-fully silent: HDAC complexes in fission yeast

  • Assen Roguev
  • , Nevan J. Krogan

Research output: Contribution to journalShort surveypeer-review

7 Scopus citations

Abstract

Proper establishment, maintenance and removal of covalent post-translational modifications on histones are essential for normal cell physiology. In this issue, Nicolas et al. describe the characterization of two physically and functionally distinct Clr6 (Rpd3)-containing histone deacetylase complexes in fission yeast and implicate their activity in a number of processes, including transcriptional regulation, silencing and genomic integrity.

Original languageEnglish
Pages (from-to)358-359
Number of pages2
JournalNature Structural and Molecular Biology
Volume14
Issue number5
DOIs
StatePublished - May 2007
Externally publishedYes

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