Simultaneous OCT/ICG fluorescence imaging system in the clinic

The authors report preliminary clinical results using a unique instrument which acquires and displays simultaneously an Optical Coherence Tomography (OCT) and an indocyanine green fluorescence image (ICGF). The two images are produced by two channels, an OCT and a confocal channel tuned to the ICG fluorescence spectrum. The system is based on our previously described ophthalmic OCT/confocal imaging system, where the same source is used to produce the OCT image and excite fluorescence in the ICG dye. The system is compact and assembled on a chin rest and it enables the clinician to visualise the same area of the eye fundus in terms of both en-face OCT slices and ICG angiograms, displayed side by side. The images are collected by fast T-scanning (en-face) which are then used to build B-scan or C-scan images. We present images of a variety of choroidal neovascular membranes, and lesions suspected of harboring choroidal neovascular membranes.