Simulating flow microfluorometry experiments with the computer language cellsim

Charles E. Donaghey; Benjamin Drewinko; Barthel Barlogie; Elton Stubblefield

doi:10.1016/0303-2647(78)90017-5

Simulating flow microfluorometry experiments with the computer language cellsim

Charles E. Donaghey
, Benjamin Drewinko
, Barthel Barlogie
, Elton Stubblefield

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

CELLSIM is a digital simulation language specifically designed for simulating cell kinetics models. Recently a flow microfluorometry (FMF) command has been added to the language. In the command, the modeler indicates when his simulated FMF analyses are to take place, and what cell states are to be included. He may specify different coefficients of variance and a non-linear DNA synthesis rate for S phase cells. The FMF capability of the language has proved to be a useful tool in several applications.

Original language	English
Pages (from-to)	339-347
Number of pages	9
Journal	BioSystems
Volume	10
Issue number	4
DOIs	https://doi.org/10.1016/0303-2647(78)90017-5
State	Published - Dec 1978
Externally published	Yes

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@article{c5239ce8d5d24e0d8b34d8cdfb26bddd,

title = "Simulating flow microfluorometry experiments with the computer language cellsim",

abstract = "CELLSIM is a digital simulation language specifically designed for simulating cell kinetics models. Recently a flow microfluorometry (FMF) command has been added to the language. In the command, the modeler indicates when his simulated FMF analyses are to take place, and what cell states are to be included. He may specify different coefficients of variance and a non-linear DNA synthesis rate for S phase cells. The FMF capability of the language has proved to be a useful tool in several applications.",

author = "Donaghey, \{Charles E.\} and Benjamin Drewinko and Barthel Barlogie and Elton Stubblefield",

note = "Funding Information: When a cell population is to be analyzed by FMF equipment, the cells are stained with a flourescent dye having specific stoichiometric affinity for DNA. The stained cells are then passed, single file, through a laser beam. During the transit across the beam a fluore- * This work was supported by National Cancer Institute Grants CA 19995-01 and CA \textbackslash{}]4528.",

year = "1978",

month = dec,

doi = "10.1016/0303-2647(78)90017-5",

language = "English",

volume = "10",

pages = "339--347",

journal = "BioSystems",

issn = "0303-2647",

publisher = "Elsevier Ireland Ltd",

number = "4",

}

TY - JOUR

T1 - Simulating flow microfluorometry experiments with the computer language cellsim

AU - Donaghey, Charles E.

AU - Drewinko, Benjamin

AU - Barlogie, Barthel

AU - Stubblefield, Elton

N1 - Funding Information: When a cell population is to be analyzed by FMF equipment, the cells are stained with a flourescent dye having specific stoichiometric affinity for DNA. The stained cells are then passed, single file, through a laser beam. During the transit across the beam a fluore- * This work was supported by National Cancer Institute Grants CA 19995-01 and CA \]4528.

PY - 1978/12

Y1 - 1978/12

N2 - CELLSIM is a digital simulation language specifically designed for simulating cell kinetics models. Recently a flow microfluorometry (FMF) command has been added to the language. In the command, the modeler indicates when his simulated FMF analyses are to take place, and what cell states are to be included. He may specify different coefficients of variance and a non-linear DNA synthesis rate for S phase cells. The FMF capability of the language has proved to be a useful tool in several applications.

AB - CELLSIM is a digital simulation language specifically designed for simulating cell kinetics models. Recently a flow microfluorometry (FMF) command has been added to the language. In the command, the modeler indicates when his simulated FMF analyses are to take place, and what cell states are to be included. He may specify different coefficients of variance and a non-linear DNA synthesis rate for S phase cells. The FMF capability of the language has proved to be a useful tool in several applications.

UR - https://www.scopus.com/pages/publications/0018245471

U2 - 10.1016/0303-2647(78)90017-5

DO - 10.1016/0303-2647(78)90017-5

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AN - SCOPUS:0018245471

SN - 0303-2647

VL - 10

SP - 339

EP - 347

JO - BioSystems

JF - BioSystems

IS - 4

ER -

Simulating flow microfluorometry experiments with the computer language cellsim

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