TY - JOUR
T1 - Simplified radioimmunoassay for viral antigens
T2 - Use of staphylococcus aureus as an adsorbent for antigen-antibody complexes: Brief communication
AU - Premkumar-Reddy, E.
AU - Devare, Sushilkumar G.
AU - Vasudev, Ratna
AU - Sarma, Padman S.
N1 - Funding Information:
2 Supported by Public Health Service (PHS) contract NOI-CP43254 from the Virus Cancer Program within the Division of Cancer Cause and Prevention, National Cancer Institute (NCI).
PY - 1977/6
Y1 - 1977/6
N2 - In a rapid method for the radioimmunoassay (RIA) of viral antigens, Staphylococcus aureus was used as the adsorbent for antigen-antibody complexes (“protein A” molecules on the cell walls of certain strains of staphylococci have a strong affinity toward IgG molecules). The results showed that this method could be used instead of the double-antibody technique, with the same or probably higher sensitivity in precipitation as well as competition RIA’s.
AB - In a rapid method for the radioimmunoassay (RIA) of viral antigens, Staphylococcus aureus was used as the adsorbent for antigen-antibody complexes (“protein A” molecules on the cell walls of certain strains of staphylococci have a strong affinity toward IgG molecules). The results showed that this method could be used instead of the double-antibody technique, with the same or probably higher sensitivity in precipitation as well as competition RIA’s.
UR - http://www.scopus.com/inward/record.url?scp=0017682968&partnerID=8YFLogxK
U2 - 10.1093/jnci/58.6.1859
DO - 10.1093/jnci/58.6.1859
M3 - Article
C2 - 864763
AN - SCOPUS:0017682968
SN - 0027-8874
VL - 58
SP - 1859
EP - 1861
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
IS - 6
ER -