Similarities and differences in allocation policies for pediatric liver transplantation across the world

Björn Fischler, Ulrich Baumann, Daniel D'Agostino, Lorenzo D'Antiga, Antal Dezsofi, Dominique Debray, Ozlem Durmaz, Helen Evans, Esteban Frauca, Nedim Hadzic, Jörg Jahnel, Jerome Loveland, Valérie McLin, Vicky L. Ng, Valerio Nobili, Joanna Pawłowska, Khalid Sharif, Francoise Smets, Henkjan J. Verkade, Evelyn HsuSimon Horslen, John Bucuvalas

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Objectives:We aimed to investigate national allocation policies for pediatric liver transplantation (LT).Method:A survey was prepared by the European Society for Paediatric Gastroenterology Hepatology and Nutrition Hepatology Committee in collaboration with the North American Studies of Pediatric Liver Transplantation consortium. The survey was sent to pediatric hepatologists and transplant surgeons worldwide. National data were obtained from centrally based registries.Results:Replies were obtained from 15 countries from 5 of the world continents. Overall donation rate varied between 9 and 35 per million inhabitants. The number of pediatric LTs was 4 to 9 per million inhabitants younger than 18 years for 13 of the 15 respondents. In children younger than 2 years mortality on the waiting list (WL) varied between 0 and 20%. In the same age group, there were large differences in the ratio of living donor LT to deceased donor LT and in the ratio of split liver segments to whole liver. These differences were associated with possible discrepancies in WL mortality.Conclusions:Similarities but also differences between countries were detected. The described data may be of importance when trying to reduce WL mortality in the youngest children.

Original languageEnglish
Pages (from-to)700-705
Number of pages6
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume68
Issue number5
DOIs
StatePublished - 1 May 2019

Keywords

  • allocation
  • deceased donor
  • liver transplantation
  • living donor
  • split liver
  • waiting list

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