Abstract
Reactive oxygen species (ROS) are generated during T cell activation and serve a signaling function but can also be damaging. In this issue of Immunity, Zhang et al. (2016) show that miR-23a prevents ROS-elicited necrosis by suppressing cyclophilin D (PPIF), a regulator of ROS escape from mitochondria.
| Original language | English |
|---|---|
| Pages (from-to) | 520-522 |
| Number of pages | 3 |
| Journal | Immunity |
| Volume | 44 |
| Issue number | 3 |
| DOIs | |
| State | Published - 15 Mar 2016 |
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