Sildenafil as a therapeutic option for digital ischemic ulceration: Case report

Swenn Maxence Krähenbühl, Michele Depairon, Marguerite Faure, Naik Vietti Violi, Lee Ann Applegate, Wassim Raffoul

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1 Scopus citations


We report the case of a 37-year-old woman who developed critical upper limb ischemia caused by a cervical rib. Because the malformation was initially undiagnosed, a vascular bypass was performed, and failure occurred. Following a 6-month therapy with sildenafil, revascularization of the arm was successful and amputation was avoided. A 6-year follow-up shows a rich collateral network at the compression site and normal values of digital plethysmography. Because hand surgeons often see patients with digital ulcerations and other manifestations of peripheral vascular pathology, therapy of ischemia with sildenafil could be an effective treatment option in patients not responding to classic drugs.

Original languageEnglish
Article number54421
Pages (from-to)890-893
Number of pages4
JournalJournal of Hand Surgery
Issue number5
StatePublished - 1 May 2015
Externally publishedYes


  • Cervical rib
  • digital necrosis
  • sildenafil
  • thoracic outlet syndrome
  • unilateral Raynaud phenomenon


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