Shear wave elastography in the detection of sinusoidal obstruction syndrome in adult patients undergoing allogenic hematopoietic stem cell transplantation

Marten Schulz, Lam Giang Vuong, Hans Peter Müller, Martin Maibier, Frank Tacke, Igor Wolfgang Blau, Alexander Wree

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Hepatic sinusoidal obstruction syndrome (SOS), also known as veno-occlusive disease (VOD) can be a life-threatening complication after hematopoietic stem cell transplantation (HSCT). Diagnosis is often difficult and traditionally based on clinical parameters. Shear wave elastography (SWE) is a modern non-invasive liver stiffness measurement technique using ultrasound. In this monocentric study, we evaluated the role of SWE in diagnosing SOS/VOD in 63 adult patients undergoing HSCT from February 2020 to August 2020 in real world settings. Three patients devel-oped SOS/VOD. This was accompanied by an increase in shear wave velocity in all three patients, indicating that this method may contribute to establishing the diagnosis SOS/VOD after HSCT.

Original languageEnglish
Article number928
JournalDiagnostics
Volume11
Issue number6
DOIs
StatePublished - Jun 2021
Externally publishedYes

Keywords

  • Hematopoietic stem cell transplantation (HSCT)
  • Liver stiffness measurement (LSM)
  • Shear wave elastography (SWE)
  • Sinusoidal obstruction syndrome (SOS)
  • Veno-occlusive disease (VOD)

Fingerprint

Dive into the research topics of 'Shear wave elastography in the detection of sinusoidal obstruction syndrome in adult patients undergoing allogenic hematopoietic stem cell transplantation'. Together they form a unique fingerprint.

Cite this