@article{0a02197f71bb44c4bed3cb2b92523761,
title = "Sexually Acquired Hepatitis C Infection in HIV-Uninfected Men Who Have Sex with Men Using Preexposure Prophylaxis against HIV",
abstract = "Sexually acquired hepatitis C virus (HCV) infections among human immunodeficiency virus (HIV)-uninfected men who have sex with men (MSM) have been rare. With the introduction of preexposure prophylaxis (PrEP) against HIV, we hypothesized that these infections would increase. Between 2013 and 2018, we diagnosed 15 likely sexually acquired HCV infections among 14 MSM using PrEP. Most (87%) were asymptomatic, detected by routine alanine transaminase (ALT) or HCV monitoring. Half reported increasing sex partners and drug use after starting PrEP; 5 reported injection of methamphetamine. Interventions are needed to prevent sexually acquired HCV infections by MSM using PrEP. Centers for Disease Control and Prevention guidelines for monitoring during PrEP should include regular ALT and HCV testing.",
keywords = "acute hepatitis C virus, men who have sex with men, methamphetamine, preexposure prophylaxis, sexual transmission",
author = "Price, {Jennifer C.} and Mckinney, {Jeffrey E.} and Crouch, {Pierre Cedric} and Dillon, {Stephen M.} and Asa Radix and Alicia Stivala and Carollo, {Jesse R.} and Fierer, {Daniel S.}",
note = "Funding Information: Potential conflicts of interest. D. S. F. reports being on the steering committee, speaker, and receiving honoraria from the Chronic Liver Disease Foundation; having been a speaker and received honoraria from the National Committee for Quality Assurance; and research funding from and shares ownership interest in Gilead Sciences, Inc. J. C. P. reports grant support from Gilead Sciences and Merck, and shares ownership interest in Abbvie, Bristol-Myers Squibb, Johnson and Johnson, and Merck & Co. All other authors report no potential conflicts. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed. Funding Information: Financial support. This work was supported by American College of Gastroenterology (Junior Faculty Development Award to J. C. P). Publisher Copyright: {\textcopyright} 2018 The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.",
year = "2019",
month = apr,
day = "16",
doi = "10.1093/infdis/jiy670",
language = "English",
volume = "219",
pages = "1373--1376",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "9",
}