Sex-Related Differences in Clinical Presentation and Risk Factors for Mortality in Patients Hospitalized with Coronavirus Disease 2019 in New York City

Jyoti S. Mathad; Myung Hee Lee; Andrea Chalem; Melissa K. Frey; Eloise Chapman-Davis; Rohini V. Kopparam; Ashlesha K. Dayal; Gal Wald; Laura C. Pinheiro; Michael J. Satlin; Parag Goyal; Monika M. Safford; Mirella Salvatore; Kevin Holcomb

doi:10.1093/ofid/ofab370

Sex-Related Differences in Clinical Presentation and Risk Factors for Mortality in Patients Hospitalized with Coronavirus Disease 2019 in New York City

Jyoti S. Mathad
, Myung Hee Lee
, Andrea Chalem
, Melissa K. Frey
, Eloise Chapman-Davis
, Rohini V. Kopparam
, Ashlesha K. Dayal
, Gal Wald
, Laura C. Pinheiro
, Michael J. Satlin
, Parag Goyal
, Monika M. Safford
, Mirella Salvatore
, Kevin Holcomb

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We evaluated sex-related differences in symptoms and risk factors for mortality in 4798 patients hospitalized with coronavirus disease 2019 in New York City. When adjusted for age and comorbidities, being male was an independent predictor of death with mortality significantly higher than females, even with low severe acute respiratory syndrome coronavirus 2 viral load at admission.

Original language	English
Article number	ofab370
Journal	Open Forum Infectious Diseases
Volume	8
Issue number	8
DOIs	https://doi.org/10.1093/ofid/ofab370
State	Published - 1 Aug 2021
Externally published	Yes

Keywords

COVID-19
mortality
risk factors
sex
viral load

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10.1093/ofid/ofab370

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Mathad, J. S., Lee, M. H., Chalem, A., Frey, M. K., Chapman-Davis, E., Kopparam, R. V., Dayal, A. K., Wald, G., Pinheiro, L. C., Satlin, M. J., Goyal, P., Safford, M. M., Salvatore, M., & Holcomb, K. (2021). Sex-Related Differences in Clinical Presentation and Risk Factors for Mortality in Patients Hospitalized with Coronavirus Disease 2019 in New York City. Open Forum Infectious Diseases, 8(8), Article ofab370. https://doi.org/10.1093/ofid/ofab370

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title = "Sex-Related Differences in Clinical Presentation and Risk Factors for Mortality in Patients Hospitalized with Coronavirus Disease 2019 in New York City",

abstract = "We evaluated sex-related differences in symptoms and risk factors for mortality in 4798 patients hospitalized with coronavirus disease 2019 in New York City. When adjusted for age and comorbidities, being male was an independent predictor of death with mortality significantly higher than females, even with low severe acute respiratory syndrome coronavirus 2 viral load at admission.",

keywords = "COVID-19, mortality, risk factors, sex, viral load",

author = "Mathad, \{Jyoti S.\} and Lee, \{Myung Hee\} and Andrea Chalem and Frey, \{Melissa K.\} and Eloise Chapman-Davis and Kopparam, \{Rohini V.\} and Dayal, \{Ashlesha K.\} and Gal Wald and Pinheiro, \{Laura C.\} and Satlin, \{Michael J.\} and Parag Goyal and Safford, \{Monika M.\} and Mirella Salvatore and Kevin Holcomb",

note = "Publisher Copyright: {\textcopyright} 2021 The Author(s).",

year = "2021",

month = aug,

day = "1",

doi = "10.1093/ofid/ofab370",

language = "English",

volume = "8",

journal = "Open Forum Infectious Diseases",

issn = "2328-8957",

publisher = "Oxford University Press",

number = "8",

}

Mathad, JS, Lee, MH, Chalem, A, Frey, MK, Chapman-Davis, E, Kopparam, RV, Dayal, AK, Wald, G, Pinheiro, LC, Satlin, MJ, Goyal, P, Safford, MM, Salvatore, M & Holcomb, K 2021, 'Sex-Related Differences in Clinical Presentation and Risk Factors for Mortality in Patients Hospitalized with Coronavirus Disease 2019 in New York City', Open Forum Infectious Diseases, vol. 8, no. 8, ofab370. https://doi.org/10.1093/ofid/ofab370

TY - JOUR

T1 - Sex-Related Differences in Clinical Presentation and Risk Factors for Mortality in Patients Hospitalized with Coronavirus Disease 2019 in New York City

AU - Mathad, Jyoti S.

AU - Lee, Myung Hee

AU - Chalem, Andrea

AU - Frey, Melissa K.

AU - Chapman-Davis, Eloise

AU - Kopparam, Rohini V.

AU - Dayal, Ashlesha K.

AU - Wald, Gal

AU - Pinheiro, Laura C.

AU - Satlin, Michael J.

AU - Goyal, Parag

AU - Safford, Monika M.

AU - Salvatore, Mirella

AU - Holcomb, Kevin

PY - 2021/8/1

Y1 - 2021/8/1

N2 - We evaluated sex-related differences in symptoms and risk factors for mortality in 4798 patients hospitalized with coronavirus disease 2019 in New York City. When adjusted for age and comorbidities, being male was an independent predictor of death with mortality significantly higher than females, even with low severe acute respiratory syndrome coronavirus 2 viral load at admission.

AB - We evaluated sex-related differences in symptoms and risk factors for mortality in 4798 patients hospitalized with coronavirus disease 2019 in New York City. When adjusted for age and comorbidities, being male was an independent predictor of death with mortality significantly higher than females, even with low severe acute respiratory syndrome coronavirus 2 viral load at admission.

KW - COVID-19

KW - mortality

KW - risk factors

KW - sex

KW - viral load

UR - https://www.scopus.com/pages/publications/85118258734

U2 - 10.1093/ofid/ofab370

DO - 10.1093/ofid/ofab370

M3 - Article

AN - SCOPUS:85118258734

SN - 2328-8957

VL - 8

JO - Open Forum Infectious Diseases

JF - Open Forum Infectious Diseases

IS - 8

M1 - ofab370

ER -

Sex-Related Differences in Clinical Presentation and Risk Factors for Mortality in Patients Hospitalized with Coronavirus Disease 2019 in New York City

Abstract

Keywords

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