Serotonin-specific drugs for anxiety and depressive disorders

D. S. Charney, J. H. Krystal, P. L. Delgado, G. R. Heninger

Research output: Contribution to journalArticlepeer-review

74 Scopus citations


In the last few years there has been a marked increase in knowledge regarding the possible roles of serotonin neuronal dysfunction in the pathophysiology and treatment of anxiety and depressive disorders. During the same time period, new drugs with specific actions on serotonin function have become available for clinical testing. This review provides an update on the efficacy of serotonin-specific drugs for anxiety and depressive disorders.

Original languageEnglish
Pages (from-to)437-446
Number of pages10
JournalAnnual Review of Medicine
Issue number1
StatePublished - 1990
Externally publishedYes


  • Depression
  • Drugs
  • Serotonin receptors


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