Serial whole-brain N-acetylaspartate concentration in healthy young adults

D. J. Rigotti, M. Inglese, J. S. Babb, M. Rovaris, B. Benedetti, M. Filippi, R. I. Grossman, Oded Gonen

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Although the concentration of N-acetylaspartate (NAA) is often used as a neuronal integrity marker, its normal temporal variations are not well documented. To assess them over the 1-2 year periods of typical clinical trials, the whole-brain NAA concentration was measured longitudinally, over 4 years, in a cohort of healthy young adults. No significant change (adjusted for both sex and age) was measured either interpersonally or intrapersonally over the entire duration of the study.

Original languageEnglish
Pages (from-to)1650-1651
Number of pages2
JournalAmerican Journal of Neuroradiology
Issue number9
StatePublished - Oct 2007
Externally publishedYes


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