TY - JOUR
T1 - Serial evaluation of right ventricular dysfunction associated with acute inferior myocardial infarction
AU - Yasuda, Tsunehiro
AU - Okada, Robert D.
AU - Leinbach, Robert C.
AU - Gold, Herman K.
AU - Phillips, Harry
AU - McKusick, Kenneth A.
AU - Glover, David K.
AU - Boucher, Charles A.
AU - William Strauss, H.
N1 - Funding Information:
From the Nuclear MedicineD ivision,D epartmento f Radiologya nd Cardiac Unit, Department of Medicine, Massachusetts General Hospital; Saint Francis Hospital Medical Research Institute Tulsa, Okla. and the University of Oklahoma Health Sciences Center, Oklahoma City, Okla. Supported in part by United States Public Health Service IschemicS COR grant No. HL26215. Received for publicationO ct. 12, 1989; accepted Dec. 1, 1989. Reprint requests: H.. William Strauss, MD, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114.
PY - 1990/4
Y1 - 1990/4
N2 - Right ventricular (RV) function was evaluated serially bymultigated blood pool imaging in 18 patients with RV dysfunction associated with acute inferior myocardial infarction. Radionuclide ventriculograms were performed on all patients within 18 hours of chest pain and again at 10 days. In addition, 15 of 18 patients had rest and exercise radionuclide ventriculogams at 3 months. The mean resting right ventricular ejection fractions (RVEF) at admission, 10 days, and 3 months in these patients was 31.8±12.6% (SD), 46.9±11.2% (p<0.05), and 44.5±10.2% (p<0.05), while the left ventricular ejection fractions were 55.9±10.6%, 57.9±13.3%, and 53.1±11.2% (p=ns). The 3-month exercise radionuclide ventriculogram demonstrated an increase in RVEF>5% in 6 of 15 patients. In eight catheterized patients, neither the location nor the severity of coronary artery narrowing nor the presence of collaterals correlated with the RV exercise response. Improvement in RV function over a 10-day interval following acute inferior myocardial infarction suggests the presence of significant reversible right ventricular dysfunction during the acute phase.
AB - Right ventricular (RV) function was evaluated serially bymultigated blood pool imaging in 18 patients with RV dysfunction associated with acute inferior myocardial infarction. Radionuclide ventriculograms were performed on all patients within 18 hours of chest pain and again at 10 days. In addition, 15 of 18 patients had rest and exercise radionuclide ventriculogams at 3 months. The mean resting right ventricular ejection fractions (RVEF) at admission, 10 days, and 3 months in these patients was 31.8±12.6% (SD), 46.9±11.2% (p<0.05), and 44.5±10.2% (p<0.05), while the left ventricular ejection fractions were 55.9±10.6%, 57.9±13.3%, and 53.1±11.2% (p=ns). The 3-month exercise radionuclide ventriculogram demonstrated an increase in RVEF>5% in 6 of 15 patients. In eight catheterized patients, neither the location nor the severity of coronary artery narrowing nor the presence of collaterals correlated with the RV exercise response. Improvement in RV function over a 10-day interval following acute inferior myocardial infarction suggests the presence of significant reversible right ventricular dysfunction during the acute phase.
UR - http://www.scopus.com/inward/record.url?scp=0025312296&partnerID=8YFLogxK
U2 - 10.1016/S0002-8703(05)80317-5
DO - 10.1016/S0002-8703(05)80317-5
M3 - Article
C2 - 2321503
AN - SCOPUS:0025312296
SN - 0002-8703
VL - 119
SP - 816
EP - 822
JO - American Heart Journal
JF - American Heart Journal
IS - 4
ER -