TY - JOUR
T1 - Sensing RNA virus infections
AU - Basler, Christopher F.
AU - García-Sastre, Adolfo
PY - 2007/1
Y1 - 2007/1
N2 - RIG-I is an RNA helicase that senses viral infections and triggers innate and adaptive immune mechanisms. Recent studies have identified RNAs bearing 5′-triphosphates as ligands of RIG-I and have suggested a mechanism for how RIG-I distinguishes viral RNA from host RNA.
AB - RIG-I is an RNA helicase that senses viral infections and triggers innate and adaptive immune mechanisms. Recent studies have identified RNAs bearing 5′-triphosphates as ligands of RIG-I and have suggested a mechanism for how RIG-I distinguishes viral RNA from host RNA.
UR - http://www.scopus.com/inward/record.url?scp=33845766166&partnerID=8YFLogxK
U2 - 10.1038/nchembio0107-20
DO - 10.1038/nchembio0107-20
M3 - Short survey
C2 - 17173024
AN - SCOPUS:33845766166
SN - 1552-4450
VL - 3
SP - 20
EP - 21
JO - Nature Chemical Biology
JF - Nature Chemical Biology
IS - 1
ER -