Selective Neuronal Vulnerability in Alzheimer's Disease: A Modern Holy Grail

Jessica Rexach, Daniel Geschwind

Research output: Contribution to journalComment/debate

3 Scopus citations

Abstract

In this issue of Neuron, through an elegant progression of computational and bio-informatic experiments centered on transcriptomic comparison of vulnerable and resistant neurons across species, Roussarie et al. (2020) predict and provide experimental support for specific genes and molecular pathways driving Alzheimer's disease, including the splicing factor PTBP1.

Original languageEnglish
Pages (from-to)763-765
Number of pages3
JournalNeuron
Volume107
Issue number5
DOIs
StatePublished - 9 Sep 2020
Externally publishedYes

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