Seeking alternative biological therapies: The future of targeted molecular treatment

Jochen H. Lorch; Marshall R. Posner; Lori J. Wirth; Robert I. Haddad

doi:10.1016/j.oraloncology.2008.08.009

Seeking alternative biological therapies: The future of targeted molecular treatment

Jochen H. Lorch, Marshall R. Posner, Lori J. Wirth, Robert I. Haddad

Research output: Contribution to journal › Review article › peer-review

12 Scopus citations

Abstract

In recent years targeted therapies have expanded treatment options for patients with squamous cell cancer of the head and neck (SCCHN) considerably and have led to clinically significant benefit. However, the multitude of new targeted drugs that have emerged and are in development also represent a challenge and many years of carefully conducted clinical studies will be needed to explore their full potential. This article summarizes the most important recent developments in the targeted treatment of SCCHN and provides an overview of pathways and promising potential targets that could impact the treatment of patients with SCCHN in the future.

Original language	English
Pages (from-to)	447-453
Number of pages	7
Journal	Oral Oncology
Volume	45
Issue number	4-5
DOIs	https://doi.org/10.1016/j.oraloncology.2008.08.009
State	Published - Apr 2009
Externally published	Yes

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10.1016/j.oraloncology.2008.08.009

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title = "Seeking alternative biological therapies: The future of targeted molecular treatment",

abstract = "In recent years targeted therapies have expanded treatment options for patients with squamous cell cancer of the head and neck (SCCHN) considerably and have led to clinically significant benefit. However, the multitude of new targeted drugs that have emerged and are in development also represent a challenge and many years of carefully conducted clinical studies will be needed to explore their full potential. This article summarizes the most important recent developments in the targeted treatment of SCCHN and provides an overview of pathways and promising potential targets that could impact the treatment of patients with SCCHN in the future.",

author = "Lorch, {Jochen H.} and Posner, {Marshall R.} and Wirth, {Lori J.} and Haddad, {Robert I.}",

year = "2009",

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T2 - The future of targeted molecular treatment

AU - Lorch, Jochen H.

AU - Posner, Marshall R.

AU - Wirth, Lori J.

AU - Haddad, Robert I.

PY - 2009/4

Y1 - 2009/4

N2 - In recent years targeted therapies have expanded treatment options for patients with squamous cell cancer of the head and neck (SCCHN) considerably and have led to clinically significant benefit. However, the multitude of new targeted drugs that have emerged and are in development also represent a challenge and many years of carefully conducted clinical studies will be needed to explore their full potential. This article summarizes the most important recent developments in the targeted treatment of SCCHN and provides an overview of pathways and promising potential targets that could impact the treatment of patients with SCCHN in the future.

AB - In recent years targeted therapies have expanded treatment options for patients with squamous cell cancer of the head and neck (SCCHN) considerably and have led to clinically significant benefit. However, the multitude of new targeted drugs that have emerged and are in development also represent a challenge and many years of carefully conducted clinical studies will be needed to explore their full potential. This article summarizes the most important recent developments in the targeted treatment of SCCHN and provides an overview of pathways and promising potential targets that could impact the treatment of patients with SCCHN in the future.

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DO - 10.1016/j.oraloncology.2008.08.009

M3 - Review article

C2 - 19027348

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SN - 1368-8375

VL - 45

SP - 447

EP - 453

JO - Oral Oncology

JF - Oral Oncology

IS - 4-5

ER -

Seeking alternative biological therapies: The future of targeted molecular treatment

Abstract

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