Second primary genital malignancies associated with endometrial cancer

G. Ohel, Z. Schwartz, A. Birkenfeld, S. O. Anteby, J. G. Schenker

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10 Scopus citations


Epidemiological data on Israeli patients with second primary genital malignancies associated with endometrial cancer is presented. During the 7 years of study, 29 (2.9%) of 1007 patients with endometrial cancer had additional primary malignancy involving the genital organs. Of these, there were 25 (2.5%) ovarian and 4 (0.4%) cervical malignancies. The occurrence of a second malignancy was related to ethnic origin. The ratio of European/American to Asian/African Jewish descendants was 8.7 to 1. A significantly greater than expected incidence of ovarian and cervical malignancy was detected in the endometrial cancer patient (P < 0.0001). The prognosis was mainly influenced by the clinical staging of disease at the time of diagnosis. Recognition of the fact that second primary cancers occur at a higher than expected frequency in patients with endometrial cancer, offers an opportunity for their early detection.

Original languageEnglish
Pages (from-to)75-80
Number of pages6
JournalArchives of Gynecology
Issue number2
StatePublished - Aug 1986
Externally publishedYes


  • Cervical cancer
  • Endometrial cancer
  • Multiple primary malignancies
  • Ovarian cancer


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