Second neoplasms in acute lymphoblastic leukemia

M. Hosein Zarrabi, Fred Rosner, Hans W. Grünwald

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

The authors reviewed 61 reported cases of second neoplasms in acute lymphoblastic leukemia (ALL), including 17 patients with ALL followed by another type of acute leukemia, 12 patients with ALL followed by chronic myelocytic leukemia, 19 patients with ALL followed by lymphoma, and 13 patients with ALL followed by other solid tumors. From a review of the literature, it is believed that there is no firm evidence yet that patients with ALL, intensively treated with chemotherapy and/or radiotherapy, are at increased risk of developing therapy‐related second neoplasms. Because the number of cases reported is small, there is even insufficient data to firmly suggest that acute myeloblastic leukemia, following intensive therapy for ALL, occurs in a higher‐than‐expected frequency.

Original languageEnglish
Pages (from-to)1712-1719
Number of pages8
JournalCancer
Volume52
Issue number9
DOIs
StatePublished - 1 Nov 1983
Externally publishedYes

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