Abstract
Although an association between exposure to bleomycin and the development of scleroderma has been suspected, few cases are reported. We describe the development of cutaneous scleroderma in 3 patients coincident with the use of bleomycin in low cumulative doses of less than 100 U. Dramatic clinical improvement occurred in 2 patients treated with high dose steroids. Our series of 3 patients supports a causal connection between bleomycin and scleroderma. In light of the widespread use of bleomycin, this complication may be under-appreciated.
Original language | English |
---|---|
Pages (from-to) | 294-296 |
Number of pages | 3 |
Journal | Journal of Rheumatology |
Volume | 19 |
Issue number | 2 |
State | Published - 1992 |
Keywords
- bleomycin
- scleroderma