Scaffold hopping approach on the route to selective tankyrase inhibitors

Keyphrases

• Tankyrase Inhibitor 100%
• Scaffold Hopping 100%
• Phenyl 66%
• Benzo 66%
• Pyrimidin-4(3H)-one 66%
• Cancer Cells 33%
• Pharmacogenetic Testing 33%
• Wnt Signaling 33%
• Screening Method 33%
• Methoxy 33%
• High Selectivity 33%
• Chemotype 33%
• Virtual Screening 33%
• Compound II 33%
• Compound Collection 33%
• Nicotinamide 33%
• Cell Growth Inhibition 33%
• Micromolar Concentration 33%
• Quinoline 33%
• Tert-butyl 33%
• New Scaffolds 33%
• DLD-1 33%
• Tankyrase 33%
• Tandem Structure 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Tankyrase Inhibitor 100%
• Tankyrase 100%
• Malignant Neoplasm 50%
• Virtual Screening 50%
• Nicotinamide 50%