Salivary acinic cell carcinoma: reappraisal and update

V. Vander Poorten; A. Triantafyllou; L. D.R. Thompson; J. Bishop; E. Hauben; J. Hunt; A. Skalova; G. Stenman; R. P. Takes; D. R. Gnepp; H. Hellquist; B. Wenig; D. Bell; A. Rinaldo; A. Ferlito

doi:10.1007/s00405-015-3855-7

Salivary acinic cell carcinoma: reappraisal and update

V. Vander Poorten
, A. Triantafyllou
, L. D.R. Thompson
, J. Bishop
, E. Hauben
, J. Hunt
, A. Skalova
, G. Stenman
, R. P. Takes
, D. R. Gnepp
, H. Hellquist
, B. Wenig
, D. Bell
, A. Rinaldo
, A. Ferlito

Research output: Contribution to journal › Review article › peer-review

91 Scopus citations

Abstract

Epidemiologic and clinicopathologic features, therapeutic strategies, and prognosis for acinic cell carcinoma of the major and minor salivary glands are critically reviewed. We explore histopathologic, histochemical, electron microscopic and immunohistochemical aspects and discuss histologic grading, histogenesis, animal models, and genetic events. In the context of possible diagnostic difficulties, the relationship to mammary analog secretory carcinoma is probed and a classification is suggested. Areas of controversy or uncertainty, which may benefit from further investigations, are also highlighted.

Original language	English
Pages (from-to)	3511-3531
Number of pages	21
Journal	European Archives of Oto-Rhino-Laryngology
Volume	273
Issue number	11
DOIs	https://doi.org/10.1007/s00405-015-3855-7
State	Published - 1 Nov 2016
Externally published	Yes

Keywords

Acinic cell carcinoma
Mammary analog secretory carcinoma
Pathology
Prognosis
Salivary glands
Therapy

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10.1007/s00405-015-3855-7

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Vander Poorten, V., Triantafyllou, A., Thompson, L. D. R., Bishop, J., Hauben, E., Hunt, J., Skalova, A., Stenman, G., Takes, R. P., Gnepp, D. R., Hellquist, H., Wenig, B., Bell, D., Rinaldo, A., & Ferlito, A. (2016). Salivary acinic cell carcinoma: reappraisal and update. European Archives of Oto-Rhino-Laryngology, 273(11), 3511-3531. https://doi.org/10.1007/s00405-015-3855-7

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abstract = "Epidemiologic and clinicopathologic features, therapeutic strategies, and prognosis for acinic cell carcinoma of the major and minor salivary glands are critically reviewed. We explore histopathologic, histochemical, electron microscopic and immunohistochemical aspects and discuss histologic grading, histogenesis, animal models, and genetic events. In the context of possible diagnostic difficulties, the relationship to mammary analog secretory carcinoma is probed and a classification is suggested. Areas of controversy or uncertainty, which may benefit from further investigations, are also highlighted.",

keywords = "Acinic cell carcinoma, Mammary analog secretory carcinoma, Pathology, Prognosis, Salivary glands, Therapy",

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note = "Publisher Copyright: {\textcopyright} 2015, Springer-Verlag Berlin Heidelberg.",

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doi = "10.1007/s00405-015-3855-7",

language = "English",

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TY - JOUR

T1 - Salivary acinic cell carcinoma

T2 - reappraisal and update

AU - Vander Poorten, V.

AU - Triantafyllou, A.

AU - Thompson, L. D.R.

AU - Bishop, J.

AU - Hauben, E.

AU - Hunt, J.

AU - Skalova, A.

AU - Stenman, G.

AU - Takes, R. P.

AU - Gnepp, D. R.

AU - Hellquist, H.

AU - Wenig, B.

AU - Bell, D.

AU - Rinaldo, A.

AU - Ferlito, A.

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Epidemiologic and clinicopathologic features, therapeutic strategies, and prognosis for acinic cell carcinoma of the major and minor salivary glands are critically reviewed. We explore histopathologic, histochemical, electron microscopic and immunohistochemical aspects and discuss histologic grading, histogenesis, animal models, and genetic events. In the context of possible diagnostic difficulties, the relationship to mammary analog secretory carcinoma is probed and a classification is suggested. Areas of controversy or uncertainty, which may benefit from further investigations, are also highlighted.

AB - Epidemiologic and clinicopathologic features, therapeutic strategies, and prognosis for acinic cell carcinoma of the major and minor salivary glands are critically reviewed. We explore histopathologic, histochemical, electron microscopic and immunohistochemical aspects and discuss histologic grading, histogenesis, animal models, and genetic events. In the context of possible diagnostic difficulties, the relationship to mammary analog secretory carcinoma is probed and a classification is suggested. Areas of controversy or uncertainty, which may benefit from further investigations, are also highlighted.

KW - Acinic cell carcinoma

KW - Mammary analog secretory carcinoma

KW - Pathology

KW - Prognosis

KW - Salivary glands

KW - Therapy

UR - https://www.scopus.com/pages/publications/84950275840

U2 - 10.1007/s00405-015-3855-7

DO - 10.1007/s00405-015-3855-7

M3 - Review article

C2 - 26685679

AN - SCOPUS:84950275840

SN - 0937-4477

VL - 273

SP - 3511

EP - 3531

JO - European Archives of Oto-Rhino-Laryngology

JF - European Archives of Oto-Rhino-Laryngology

IS - 11

ER -

Salivary acinic cell carcinoma: reappraisal and update

Abstract

Keywords

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