Safety and Efficacy of Long-Term Tocolysis with Indomethacin

Andrew Gerson; Soraya Abbasi; Anthony Johnson; Mark Kalchbrenner; Graham Ashmead; Ronald Bolognese

doi:10.1055/s-2007-999450

Safety and Efficacy of Long-Term Tocolysis with Indomethacin

Andrew Gerson, Soraya Abbasi, Anthony Johnson, Mark Kalchbrenner, Graham Ashmead, Ronald Bolognese

Research output: Contribution to journal › Article › peer-review

47 Scopus citations

Abstract

Indomethacin was utilized in 24 pregnancies (31 exposed fetuses) in preterm labor who labored despite intravenous tocolysis. The mean gestational age at the start of indomethacin therapy was 25.1 weeks (±4.4), mean duration of indomethacin therapy was 43.9 days (±31.4), mean gestational age at delivery 33.1 weeks (±3.7). Neonatal follow-up revealed the same incidence of complications in these indomethacin-exposed infants, when they were compared with all other infants born in the same time period and exposed to intravenous tocolytics only when matched for gestational age at delivery.

Original language	English
Pages (from-to)	71-74
Number of pages	4
Journal	American Journal of Perinatology
Volume	7
Issue number	1
DOIs	https://doi.org/10.1055/s-2007-999450
State	Published - Jan 1990
Externally published	Yes

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abstract = "Indomethacin was utilized in 24 pregnancies (31 exposed fetuses) in preterm labor who labored despite intravenous tocolysis. The mean gestational age at the start of indomethacin therapy was 25.1 weeks (±4.4), mean duration of indomethacin therapy was 43.9 days (±31.4), mean gestational age at delivery 33.1 weeks (±3.7). Neonatal follow-up revealed the same incidence of complications in these indomethacin-exposed infants, when they were compared with all other infants born in the same time period and exposed to intravenous tocolytics only when matched for gestational age at delivery.",

author = "Andrew Gerson and Soraya Abbasi and Anthony Johnson and Mark Kalchbrenner and Graham Ashmead and Ronald Bolognese",

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AU - Johnson, Anthony

AU - Kalchbrenner, Mark

AU - Ashmead, Graham

AU - Bolognese, Ronald

PY - 1990/1

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AB - Indomethacin was utilized in 24 pregnancies (31 exposed fetuses) in preterm labor who labored despite intravenous tocolysis. The mean gestational age at the start of indomethacin therapy was 25.1 weeks (±4.4), mean duration of indomethacin therapy was 43.9 days (±31.4), mean gestational age at delivery 33.1 weeks (±3.7). Neonatal follow-up revealed the same incidence of complications in these indomethacin-exposed infants, when they were compared with all other infants born in the same time period and exposed to intravenous tocolytics only when matched for gestational age at delivery.

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Safety and Efficacy of Long-Term Tocolysis with Indomethacin

Abstract

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