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Safety and Efficacy of Bivalirudin With and Without Glycoprotein IIb/IIIa Inhibitors in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention. 1-Year Results From the ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) Trial

  • Harvey D. White
  • , E. Magnus Ohman
  • , A. Michael Lincoff
  • , Michel E. Bertrand
  • , Antonio Colombo
  • , Brent T. McLaurin
  • , David A. Cox
  • , Stuart J. Pocock
  • , James A. Ware
  • , Steven V. Manoukian
  • , Alexandra J. Lansky
  • , Roxana Mehran
  • , Jeffrey W. Moses
  • , Gregg W. Stone

Research output: Contribution to journalArticlepeer-review

84 Scopus citations

Abstract

Objectives: This study was designed to determine the impact of bivalirudin on 1-year outcomes in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). Background: The ACUITY (Acute Catheterization and Urgent Intervention Triage strategY) trial demonstrated that in moderate- and high-risk ACS patients undergoing PCI, bivalirudin alone compared to unfractionated heparin (UFH) or enoxaparin plus a glycoprotein (GP) IIb/IIIa inhibitor resulted in less major bleeding and similar ischemic outcomes at 30 days.

Original languageEnglish
Pages (from-to)807-814
Number of pages8
JournalJournal of the American College of Cardiology
Volume52
Issue number10
DOIs
StatePublished - 2 Sep 2008
Externally publishedYes

Keywords

  • bivalirudin
  • enoxaparin
  • unfractionated heparin

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