S100-negative indeterminate cell histiocytosis in an African American child responsive to narrowband ultraviolet B

Susan Bard, Daniele Torchia, Elizabeth A. Connelly, Ana M. Duarte, Evangelos V. Badiavas, Lawrence A. Schachner

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Indeterminate cell histiocytosis is a rare cutaneous disease characterized by the presence of dendritic cells that lack Birbeck granules and immunophenotypically shares features of both Langerhans cells and macrophages. We describe a case of a 4-year-old African American boy affected by a disseminated, exclusively mucocutaneous form of indeterminate cell histiocytosis. The eruption was successfully treated with narrowband ultraviolet B. The peculiar negativity of the Langerhans cell marker S100 is also discussed.

Original languageEnglish
Pages (from-to)524-527
Number of pages4
JournalPediatric Dermatology
Volume28
Issue number5
DOIs
StatePublished - Sep 2011
Externally publishedYes

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