Roscoe Owen Brady, MD: Remembrances of co-investigators and colleagues

Robert J. Desnick, Norman W. Barton, Scott Furbish, Gregory A. Grabowski, Stefan Karlsson, Edwin H. Kolodny, Jeffrey A. Medin, Gary J. Murray, Pramod K. Mistry, Marc C. Patterson, Raphael Schiffmann, Neal J. Weinreb

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


To celebrate the research visions and accomplishments of the late Roscoe O. Brady (1923–2016), remembrance commentaries were requested from several of his postdoctoral research fellows and colleagues. These commentaries not only reflect on the accomplishments of Dr. Brady, but they also share some of the backstories and experiences working in the Brady laboratory. They provide insights and perspectives on Brady's research activities, and especially on his efforts to develop an effective treatment for patients with Type 1 Gaucher disease. These remembrances illuminate Brady's efforts to implement the latest scientific advances with an outstanding team of young co-investigators to develop and demonstrate the safety and effectiveness of the first enzyme replacement therapy for a lysosomal storage disease. Brady's pursuit and persistence in accomplishing his research objectives provide insights into this remarkably successful physician scientist who paved the way for the development of treatments for patients with other lysosomal storage diseases.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalMolecular Genetics and Metabolism
Issue number1-2
StatePublished - 1 Jan 2017


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