Role of renal biopsy in end stage renal failure

Kenneth A. Kropp, Ronald S. Shapiro, Jagadish S. Jhunjhunwala

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


The role of renal biopsy in 46 patients with end stage renal failure was assessed. Renal tissue was obtained by open renal biopsy in 24 patients, by needle biopsy in 5, and at bilateral nephrectomy in 17. In 4 patients the renal biopsy specimens showed advanced changes that could only be diagnosed as "end stage kidney." In 42 patients (91 per cent), a precise renal diagnosis was made I n 20 patients (43 per cent) the prebiopsy clinical impression differed from the histologic diagnosis. In the 29 patients undergoing renal biopsy, minor postoperative morbidity occurred in 5. We conclude that a renal biopsy in patients with end stage renal failure will result in a change in clinical diagnosis in a significant number of patients and can be performed with low morbidity.

Original languageEnglish
Pages (from-to)631-634
Number of pages4
Issue number6
StatePublished - Dec 1978
Externally publishedYes


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