[Role of miR-145 in erectile dysfunction in diabetic rats].

An yang Wei, Yong Yang, Shu hua He, Xin gui Luo, Tao Zhang, Yang Liu

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

To investigate the role of miR-145 in the corpus cavernosum smooth muscle tissue in the pathogenesis of erectile dysfunction (ED) in diabetic rats. The total RNA was extracted from the corpus cavernosum of a diabetic rat model with ED, diabetic rats with normal erectile function and normal rats, and the expression levels of miR145 were compared between the groups. The expression of miR-145 was decreased in the corpus cavernosum of diabetic rats with ED. Diabetes mellitus can cause ED in rats, in which process decreased expression of miR145 in the corpus cavernosum may play a role.

Original languageEnglish
Pages (from-to)1051-1054
Number of pages4
JournalNan fang yi ke da xue xue bao = Journal of Southern Medical University
Volume31
Issue number6
StatePublished - Jun 2011
Externally publishedYes

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