Rituximab-vincristine chemotherapy-induced acute anterior wall myocardial infarction: With cardiogenic shock

Ambuj Roy, Naveen Khanna, Nagendra Boopathy Senguttuvan

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

We present a case of an elderly man with coronary artery disease who was diagnosed with non-Hodgkin lymphoma. Soon after the administration of chemotherapy, which included rituximab and vincristine, he developed acute myocardial infarction with cardiogenic shock. The condition was managed successfully with primary percutaneous coronary intervention. We briefly discuss the possible pathogenic mechanisms of chemotherapyinduced ischemic syndrome and the management of chemotherapy in patients with high cardiovascular risk.

Original languageEnglish
Pages (from-to)80-82
Number of pages3
JournalTexas Heart Institute Journal
Volume41
Issue number1
DOIs
StatePublished - Feb 2014
Externally publishedYes

Keywords

  • Acute coronary syndrome/chemically induced
  • Acute myocardial infarction/chemically induced
  • Antineoplastic agents/toxicity
  • Cardiotoxins
  • Endothelium
  • Lymphoma
  • Non-hodgkin
  • Percutaneous coronary intervention
  • Rituximab/adverse effects
  • Tubulin/metabolism
  • Vascular/drug effects
  • Vincristine/adverse effects

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