Risk of seizure during pregnancy

Ajith Cherian, John C. DeToledo, Sahawat Tantikittichaikul, Sanjeev V. Thomas, C. L. Harden

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

A 28-year-old woman presents to your office for consultation. She has been married for 2 years and is planning to start a family and become pregnant. She is diagnosed with partial epilepsy of temporal lobe origin 5 years ago and her seizures are controlled on lamotrigine 100 mg twice daily with no recurrence in the last year. She is worried about the risk of seizure medications to her baby should she become pregnant. She wants to stop taking lamotrigine during her pregnancy. How do you counsel her regarding the risk of seizure recurrence during pregnancy and potential seizure-related complications for her future pregnancy?.

Original languageEnglish
Title of host publicationControversies in Caring for Women with Epilepsy
Subtitle of host publicationSorting Through the Evidence
PublisherSpringer International Publishing
Pages45-53
Number of pages9
ISBN (Electronic)9783319291703
ISBN (Print)9783319291680
DOIs
StatePublished - 1 Jan 2016
Externally publishedYes

Keywords

  • Antiepileptics
  • Complex partial seizures
  • Drug compliance
  • Glucuronidation
  • Lamotrigine
  • Orofacial clefts
  • Pregnancy registry
  • Serum concentration
  • Temporal CPS
  • Teratogenic risk

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