TY - JOUR
T1 - Risk Factors for Delta Hepatitis in a North American Cohort
T2 - Who Should Be Screened?
AU - Da, Ben L.
AU - Rahman, Farial
AU - Lai, Walter C.
AU - Kleiner, David E.
AU - Heller, Theo
AU - Koh, Christopher
N1 - Publisher Copyright:
© 2021 Wolters Kluwer Health. All rights reserved.
PY - 2021/1/1
Y1 - 2021/1/1
N2 - INTRODUCTION:The American Association for the Study of Liver Diseases recommends hepatitis D virus (HDV) screening in certain high-risk groups; however, the effectiveness is unknown.METHODS:A study of North American patients with hepatitis B (HBV) referred to the NIH was performed to identify risk factors associated with HDV infection. Active HDV was "confirmed" by serum HDV RNA or histologic HDV antigen staining.RESULTS:Six hundred fifty-two were studied, of which 91 were HDV "confirmed." Independent risk factors for HDV included: intravenous drug users, HBV-DNA <2,000 IU/mL, alanine aminotransferase >40 U/L, and HDV endemic country of origin.DISUSSION:North American patients with HBV and significant risk factors should be screened for HDV.
AB - INTRODUCTION:The American Association for the Study of Liver Diseases recommends hepatitis D virus (HDV) screening in certain high-risk groups; however, the effectiveness is unknown.METHODS:A study of North American patients with hepatitis B (HBV) referred to the NIH was performed to identify risk factors associated with HDV infection. Active HDV was "confirmed" by serum HDV RNA or histologic HDV antigen staining.RESULTS:Six hundred fifty-two were studied, of which 91 were HDV "confirmed." Independent risk factors for HDV included: intravenous drug users, HBV-DNA <2,000 IU/mL, alanine aminotransferase >40 U/L, and HDV endemic country of origin.DISUSSION:North American patients with HBV and significant risk factors should be screened for HDV.
UR - https://www.scopus.com/pages/publications/85099321312
U2 - 10.14309/ajg.0000000000000954
DO - 10.14309/ajg.0000000000000954
M3 - Article
C2 - 33027083
AN - SCOPUS:85099321312
SN - 0002-9270
VL - 116
SP - 206
EP - 209
JO - American Journal of Gastroenterology
JF - American Journal of Gastroenterology
IS - 1
ER -