TY - JOUR
T1 - Risk factors associated with curiosity about alcohol use in the ABCD cohort
AU - Wade, Natasha E.
AU - Palmer, Clare E.
AU - Gonzalez, Marybel R.
AU - Wallace, Alexander L.
AU - Infante, M. Alejandra
AU - Tapert, Susan F.
AU - Jacobus, Joanna
AU - Bagot, Kara S.
N1 - Funding Information:
This work was supported by T32 AA013525 (PI: Riley/Tapert to Wade), U01DA041089 (PI: Tapert/Jacobus), NIH / NIDA R21 DA047953 (PI: Jacobus), and California Tobacco-Related Disease Research Grants Program Office of the University of California Grant 580264 (PI: Jacobus).
Funding Information:
Participants and their parents completed baseline (ages 9–10) and 1-Year follow-up (ages 10–11) assessments in the ABCD Study®, a 21-site 10-year longitudinal study with 11,880 participants funded by the National Institutes of Health (Volkow et al., 2018). They were assessed on a range of behavioral, psychosocial, and cognitive risk factors related to early substance use experiences and curiosity about alcohol use. Cross-sectional data from ABCD Data Release 2.0.1 was used, containing the first half of the Year 1 follow-up data. Data in the 2.0.1 release contained available data from 4,951 participants, of which 2,334 participants were included in the present analyses, as they had never used alcohol and had no missing data on key variables. All aspects of the ABCD protocol were approved by the Institutional Review Board.This work was supported by T32 AA013525 (PI: Riley/Tapert to Wade), U01DA041089 (PI: Tapert/Jacobus), NIH/NIDA R21 DA047953 (PI: Jacobus), and California Tobacco-Related Disease Research Grants Program Office of the University of California Grant 580264 (PI: Jacobus). The ABCD Study is supported by the National Institutes of Health and additional federal partners under award numbers U01DA041022, U01DA041028, U01DA041048, U01DA041089, U01DA041106, U01DA041117, U01DA041120, U01DA041134, U01DA041148, U01DA041156, U01DA041174, U24DA041123, and U24DA041147. Data used in the preparation of this article were obtained from the Adolescent Brain Cognitive Development (ABCD) Study (https://abcdstudy.org), held in the NIMH Data Archive (NDA). This is a multisite, longitudinal study designed to recruit more than 10,000 children age 9–10 and follow them over 10 years into early adulthood. A full list of supporters is available at https://abcdstudy.org/federal-partners.html. A listing of participating sites and a complete listing of the study investigators can be found at https://abcdstudy.org/study-sites/. ABCD consortium investigators designed and implemented the study and/or provided data but did not necessarily participate in analysis or writing of this report. This manuscript reflects the views of the authors and may not reflect the opinions or views of the NIH or ABCD consortium investigators. The ABCD data repository grows and changes over time. The ABCD data used in this report came from Annual Release 2.0.1, doi: 10.15154/1503209. DOIs can be found at https://ndar.nih.gov/study.html?id=576.
Funding Information:
The ABCD Study is supported by the National Institutes of Health and additional federal partners under award numbers U01DA041022, U01DA041028, U01DA041048, U01DA041089, U01DA041106, U01DA041117, U01DA041120, U01DA041134, U01DA041148, U01DA041156, U01DA041174, U24DA041123, and U24DA041147.
Publisher Copyright:
© 2021 Elsevier Inc.
PY - 2021/5
Y1 - 2021/5
N2 - Curiosity and intent to use alcohol in pre-adolescence is a risk factor for later experimentation and use, yet we know little of how curiosity about use develops. Here, we examine factors that may influence curiosity about alcohol use, as it may be an important predictor of later drinking behavior. Cross-sectional data on youth ages 10–11 from the ongoing Adolescent Brain Cognitive Development℠ (ABCD) Study Year 1 follow-up were used (n = 2,334; NDA 2.0.1). All participants were substance-naïve at time of assessment. Group factor analysis identified latent factors across common indicators of risk for early substance use (i.e., psychopathology and trait characteristics; substance use attitudes/behaviors; neurocognition; family and environment). Logistic mixed-effect models tested associations between latent factors of risk for early substance use and curiosity about alcohol use, controlling for demographics and study site. Two multidimensional factors were significantly inversely and positively associated with greater curiosity about alcohol use, respectively: 1) low internalizing and externalizing symptomatology coupled with low impulsivity, perceived neighborhood safety, negative parental history of alcohol use problems, and fewer adverse life experiences and family conflict; and 2) low perceived risk of alcohol use coupled with lack of peer disapproval of use. When assessing all risk factors in an overall regression, lack of perceived harm from trying alcohol once or twice was associated with greater likelihood of alcohol curiosity. Taken together, perceptions that alcohol use causes little harm and having peers with similar beliefs is related to curiosity about alcohol use among substance-naïve 10–11-year-olds. General mental health and environmental risk factors similarly increase the odds of curiosity for alcohol. Identification of multidimensional risk factors for early alcohol use may point to novel prevention and early intervention targets. Future longitudinal investigations in the ABCD cohort will determine the extent to which these factors and curiosity predict alcohol use among youth.
AB - Curiosity and intent to use alcohol in pre-adolescence is a risk factor for later experimentation and use, yet we know little of how curiosity about use develops. Here, we examine factors that may influence curiosity about alcohol use, as it may be an important predictor of later drinking behavior. Cross-sectional data on youth ages 10–11 from the ongoing Adolescent Brain Cognitive Development℠ (ABCD) Study Year 1 follow-up were used (n = 2,334; NDA 2.0.1). All participants were substance-naïve at time of assessment. Group factor analysis identified latent factors across common indicators of risk for early substance use (i.e., psychopathology and trait characteristics; substance use attitudes/behaviors; neurocognition; family and environment). Logistic mixed-effect models tested associations between latent factors of risk for early substance use and curiosity about alcohol use, controlling for demographics and study site. Two multidimensional factors were significantly inversely and positively associated with greater curiosity about alcohol use, respectively: 1) low internalizing and externalizing symptomatology coupled with low impulsivity, perceived neighborhood safety, negative parental history of alcohol use problems, and fewer adverse life experiences and family conflict; and 2) low perceived risk of alcohol use coupled with lack of peer disapproval of use. When assessing all risk factors in an overall regression, lack of perceived harm from trying alcohol once or twice was associated with greater likelihood of alcohol curiosity. Taken together, perceptions that alcohol use causes little harm and having peers with similar beliefs is related to curiosity about alcohol use among substance-naïve 10–11-year-olds. General mental health and environmental risk factors similarly increase the odds of curiosity for alcohol. Identification of multidimensional risk factors for early alcohol use may point to novel prevention and early intervention targets. Future longitudinal investigations in the ABCD cohort will determine the extent to which these factors and curiosity predict alcohol use among youth.
KW - alcohol
KW - alcohol curiosity
KW - children
KW - intent to use
KW - pre-adolescent
UR - http://www.scopus.com/inward/record.url?scp=85101399919&partnerID=8YFLogxK
U2 - 10.1016/j.alcohol.2021.01.002
DO - 10.1016/j.alcohol.2021.01.002
M3 - Article
C2 - 33434614
AN - SCOPUS:85101399919
SN - 0741-8329
VL - 92
SP - 11
EP - 19
JO - Alcohol
JF - Alcohol
ER -