Right ventricular wall mechanics in normals and patients with pulmonary hypertension using magnetic resonance tissue tagging

Zahi A. Fayad; Victor A. Ferrari; Dara L. Kraitchman; Alistair A. Young; Daniel C. Bloomgarden; Leon Axel

Right ventricular wall mechanics in normals and patients with pulmonary hypertension using magnetic resonance tissue tagging

Zahi A. Fayad, Victor A. Ferrari, Dara L. Kraitchman, Alistair A. Young, Daniel C. Bloomgarden, Leon Axel

Research output: Contribution to journal › Conference article › peer-review

Abstract

Right ventricular hypertrophy (RVH) and RV dysfunction are difficult to evaluate due to the complex shape of the RV and prognostic limitations of conventional global function parameters. We used MRI with magnetization tagging to measure 2-D systolic motion and deformation of the right ventricular free wall (RVFW) and septum (SEPT) in 5 patients with RVH secondary to pulmonary hypertension, and 12 normal volunteers (NL). Regional displacement (D) and 2-D principal strains in the short-axis plane were averaged at basal, midventricular and apical levels. SEPT D was severely decreased at all levels in RVH vs. NL (P < 0.005). In RVH, RVFW D was higher than SEPT D (P < 0.02). The 2-D strains were reduced in SEPT at all levels in RVH vs. NL (P < 0.05). This technique may permit the study of progression and regression of RVH in various disease states.

Original language	English
Pages (from-to)	233-236
Number of pages	4
Journal	Computers in Cardiology
State	Published - 1995
Externally published	Yes
Event	Proceedings of the 1995 Conference on Computers in Cardiology - Vienna, Austria Duration: 10 Sep 1995 → 13 Sep 1995

Cite this

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title = "Right ventricular wall mechanics in normals and patients with pulmonary hypertension using magnetic resonance tissue tagging",

abstract = "Right ventricular hypertrophy (RVH) and RV dysfunction are difficult to evaluate due to the complex shape of the RV and prognostic limitations of conventional global function parameters. We used MRI with magnetization tagging to measure 2-D systolic motion and deformation of the right ventricular free wall (RVFW) and septum (SEPT) in 5 patients with RVH secondary to pulmonary hypertension, and 12 normal volunteers (NL). Regional displacement (D) and 2-D principal strains in the short-axis plane were averaged at basal, midventricular and apical levels. SEPT D was severely decreased at all levels in RVH vs. NL (P < 0.005). In RVH, RVFW D was higher than SEPT D (P < 0.02). The 2-D strains were reduced in SEPT at all levels in RVH vs. NL (P < 0.05). This technique may permit the study of progression and regression of RVH in various disease states.",

author = "Fayad, {Zahi A.} and Ferrari, {Victor A.} and Kraitchman, {Dara L.} and Young, {Alistair A.} and Bloomgarden, {Daniel C.} and Leon Axel",

year = "1995",

language = "English",

pages = "233--236",

journal = "Computing in Cardiology",

issn = "2325-8861",

publisher = "IEEE Computer Society",

note = "null ; Conference date: 10-09-1995 Through 13-09-1995",

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TY - JOUR

T1 - Right ventricular wall mechanics in normals and patients with pulmonary hypertension using magnetic resonance tissue tagging

AU - Fayad, Zahi A.

AU - Ferrari, Victor A.

AU - Kraitchman, Dara L.

AU - Young, Alistair A.

AU - Bloomgarden, Daniel C.

AU - Axel, Leon

PY - 1995

Y1 - 1995

N2 - Right ventricular hypertrophy (RVH) and RV dysfunction are difficult to evaluate due to the complex shape of the RV and prognostic limitations of conventional global function parameters. We used MRI with magnetization tagging to measure 2-D systolic motion and deformation of the right ventricular free wall (RVFW) and septum (SEPT) in 5 patients with RVH secondary to pulmonary hypertension, and 12 normal volunteers (NL). Regional displacement (D) and 2-D principal strains in the short-axis plane were averaged at basal, midventricular and apical levels. SEPT D was severely decreased at all levels in RVH vs. NL (P < 0.005). In RVH, RVFW D was higher than SEPT D (P < 0.02). The 2-D strains were reduced in SEPT at all levels in RVH vs. NL (P < 0.05). This technique may permit the study of progression and regression of RVH in various disease states.

AB - Right ventricular hypertrophy (RVH) and RV dysfunction are difficult to evaluate due to the complex shape of the RV and prognostic limitations of conventional global function parameters. We used MRI with magnetization tagging to measure 2-D systolic motion and deformation of the right ventricular free wall (RVFW) and septum (SEPT) in 5 patients with RVH secondary to pulmonary hypertension, and 12 normal volunteers (NL). Regional displacement (D) and 2-D principal strains in the short-axis plane were averaged at basal, midventricular and apical levels. SEPT D was severely decreased at all levels in RVH vs. NL (P < 0.005). In RVH, RVFW D was higher than SEPT D (P < 0.02). The 2-D strains were reduced in SEPT at all levels in RVH vs. NL (P < 0.05). This technique may permit the study of progression and regression of RVH in various disease states.

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M3 - Conference article

AN - SCOPUS:0029548053

SP - 233

EP - 236

JO - Computing in Cardiology

JF - Computing in Cardiology

SN - 2325-8861

Y2 - 10 September 1995 through 13 September 1995

ER -

Right ventricular wall mechanics in normals and patients with pulmonary hypertension using magnetic resonance tissue tagging

Abstract

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