Rice protein-induced enterocolitis syndrome with transient specific IgE to boiled rice but not to retort-processed rice

Motoko Yasutomi, Takuya Kosaka, Akiko Kawakita, Hisako Hayashi, Shintaro Okazaki, Hiroki Murai, Kazuhiko Miyagawa, Mitsufumi Mayumi, Yusei Ohshima

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3 Scopus citations


Described herein is the case of an 8-month-old girl with atypical food protein-induced enterocolitis syndrome due to rice. She presented with vomiting and poor general activity 2 h after ingestion of boiled rice. Oral food challenge test using high-pressure retort-processed rice was negative, but re-exposure to boiled rice elicited gastrointestinal symptoms. On western blot analysis the patient's serum was found to contain IgE bound to crude protein extracts from rice seed or boiled rice, but not from retort-processed rice. The major protein bands were not detected in the electrophoresed gel of retort-processed rice extracts, suggesting decomposition by high-temperature and high-pressure processing. Oral food challenge for diagnosing rice allergy should be performed with boiled rice to avoid a false negative. Additionally, some patients with rice allergy might be able to ingest retort-processed rice as a substitute for boiled rice.

Original languageEnglish
Pages (from-to)110-112
Number of pages3
JournalPediatrics International
Issue number1
StatePublished - Feb 2014
Externally publishedYes


  • allergen
  • allergy
  • food protein-induced enterocolitis syndrome
  • rice
  • western blot

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