Rheumatoid arthritis vs osteoarthritis in patients receiving total knee arthroplasty: Perioperative outcomes

Ottokar Stundner; Thomas Danninger; Ya Lin Chiu; Xuming Sun; Susan M. Goodman; Linda A. Russell; Mark Figgie; Madhu Mazumdar; Stavros G. Memtsoudis

doi:10.1016/j.arth.2013.05.008

Rheumatoid arthritis vs osteoarthritis in patients receiving total knee arthroplasty: Perioperative outcomes

Ottokar Stundner, Thomas Danninger, Ya Lin Chiu, Xuming Sun, Susan M. Goodman, Linda A. Russell, Mark Figgie, Madhu Mazumdar, Stavros G. Memtsoudis

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

There is a paucity of data available on perioperative outcomes of patients undergoing total knee arthroplasty (TKA) for rheumatoid arthritis (RA). We determined differences in demographics and risk for perioperative adverse events between patients suffering from osteoarthritis (OA) versus RA using a population-based approach. Of 351,103 entries for patients who underwent TKA, 3.4% had a diagnosis of RA. RA patients were on average younger [RA: 64.3. years vs OA: 66.6. years; P<. 0.001] and more likely female [RA: 79.2% vs OA: 63.2%; P<. 0. 001]. The unadjusted rates of mortality and most major perioperative adverse events were similar in both groups, with the exception of infection [RA: 4.5% vs. OA: 3.8%; P<. 0.001]. RA was not associated with increased adjusted odds for combined adverse events.

Original language	English
Pages (from-to)	308-313
Number of pages	6
Journal	Journal of Arthroplasty
Volume	29
Issue number	2
DOIs	https://doi.org/10.1016/j.arth.2013.05.008
State	Published - Feb 2014
Externally published	Yes

Keywords

Arthroplasty knee
Osteoarthritis
Outcomes research
Rheumatoid arthritis

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10.1016/j.arth.2013.05.008

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@article{830bb793831646cead40077efc4fed21,

title = "Rheumatoid arthritis vs osteoarthritis in patients receiving total knee arthroplasty: Perioperative outcomes",

abstract = "There is a paucity of data available on perioperative outcomes of patients undergoing total knee arthroplasty (TKA) for rheumatoid arthritis (RA). We determined differences in demographics and risk for perioperative adverse events between patients suffering from osteoarthritis (OA) versus RA using a population-based approach. Of 351,103 entries for patients who underwent TKA, 3.4% had a diagnosis of RA. RA patients were on average younger [RA: 64.3. years vs OA: 66.6. years; P<. 0.001] and more likely female [RA: 79.2% vs OA: 63.2%; P<. 0. 001]. The unadjusted rates of mortality and most major perioperative adverse events were similar in both groups, with the exception of infection [RA: 4.5% vs. OA: 3.8%; P<. 0.001]. RA was not associated with increased adjusted odds for combined adverse events.",

keywords = "Arthroplasty knee, Osteoarthritis, Outcomes research, Rheumatoid arthritis",

author = "Ottokar Stundner and Thomas Danninger and Chiu, {Ya Lin} and Xuming Sun and Goodman, {Susan M.} and Russell, {Linda A.} and Mark Figgie and Madhu Mazumdar and Memtsoudis, {Stavros G.}",

note = "Funding Information: Funding: This study was performed with funds from the Hospital for Special Surgery, Department of Anesthesiology, New York, NY, and the Anna-Maria and Stephen Kellen Physician-Scientist Career Development Award, New York, NY (Stavros G. Memtsoudis). Contribution of Dr. Mazumdar and Ms. Chiu on this project was supported in part by funds from the Clinical Translational Science Center (CTSC), National Center for Advancing Translational Sciences (NCATS) grant # UL1-RR024996 and Center for Education, Research, and Therapeutics (CERTs), Agency for Healthcare Research and Quality (AHRQ) grant # U18 HSO16-75. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding sources NCATS and AHRQ based in Rockville, MD. ",

year = "2014",

month = feb,

doi = "10.1016/j.arth.2013.05.008",

language = "English",

volume = "29",

pages = "308--313",

journal = "Journal of Arthroplasty",

issn = "0883-5403",

publisher = "Elsevier B.V.",

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T2 - Perioperative outcomes

AU - Stundner, Ottokar

AU - Danninger, Thomas

AU - Chiu, Ya Lin

AU - Sun, Xuming

AU - Goodman, Susan M.

AU - Russell, Linda A.

AU - Figgie, Mark

AU - Mazumdar, Madhu

AU - Memtsoudis, Stavros G.

N1 - Funding Information: Funding: This study was performed with funds from the Hospital for Special Surgery, Department of Anesthesiology, New York, NY, and the Anna-Maria and Stephen Kellen Physician-Scientist Career Development Award, New York, NY (Stavros G. Memtsoudis). Contribution of Dr. Mazumdar and Ms. Chiu on this project was supported in part by funds from the Clinical Translational Science Center (CTSC), National Center for Advancing Translational Sciences (NCATS) grant # UL1-RR024996 and Center for Education, Research, and Therapeutics (CERTs), Agency for Healthcare Research and Quality (AHRQ) grant # U18 HSO16-75. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding sources NCATS and AHRQ based in Rockville, MD.

PY - 2014/2

Y1 - 2014/2

N2 - There is a paucity of data available on perioperative outcomes of patients undergoing total knee arthroplasty (TKA) for rheumatoid arthritis (RA). We determined differences in demographics and risk for perioperative adverse events between patients suffering from osteoarthritis (OA) versus RA using a population-based approach. Of 351,103 entries for patients who underwent TKA, 3.4% had a diagnosis of RA. RA patients were on average younger [RA: 64.3. years vs OA: 66.6. years; P<. 0.001] and more likely female [RA: 79.2% vs OA: 63.2%; P<. 0. 001]. The unadjusted rates of mortality and most major perioperative adverse events were similar in both groups, with the exception of infection [RA: 4.5% vs. OA: 3.8%; P<. 0.001]. RA was not associated with increased adjusted odds for combined adverse events.

AB - There is a paucity of data available on perioperative outcomes of patients undergoing total knee arthroplasty (TKA) for rheumatoid arthritis (RA). We determined differences in demographics and risk for perioperative adverse events between patients suffering from osteoarthritis (OA) versus RA using a population-based approach. Of 351,103 entries for patients who underwent TKA, 3.4% had a diagnosis of RA. RA patients were on average younger [RA: 64.3. years vs OA: 66.6. years; P<. 0.001] and more likely female [RA: 79.2% vs OA: 63.2%; P<. 0. 001]. The unadjusted rates of mortality and most major perioperative adverse events were similar in both groups, with the exception of infection [RA: 4.5% vs. OA: 3.8%; P<. 0.001]. RA was not associated with increased adjusted odds for combined adverse events.

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ER -

Rheumatoid arthritis vs osteoarthritis in patients receiving total knee arthroplasty: Perioperative outcomes

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