Retreatment of Recurrent or Second Primary Head and Neck Cancer After Prior Radiation: Executive Summary of the American Radium Society Appropriate Use Criteria

Matthew C. Ward, Shlomo A. Koyfman, Richard L. Bakst, Danielle N. Margalit, Beth M. Beadle, Jonathan J. Beitler, Steven Shih Wei Chang, Jay S. Cooper, Thomas J. Galloway, John A. Ridge, Jared R. Robbins, Assuntina G. Sacco, C. Jillian Tsai, Sue S. Yom, Farzan Siddiqui

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

Retreatment of recurrent or second primary head and neck cancers occurring in a previously irradiated field is complex. Few guidelines exist to support practice. We performed an updated literature search of peer-reviewed journals in a systematic fashion. Search terms, key questions, and associated clinical case variants were formed by panel consensus. The literature search informed the committee during a blinded vote on the appropriateness of treatment options via the modified Delphi method. The final number of citations retained for review was 274. These informed 5 key questions, which focused on patient selection, adjuvant reirradiation, definitive reirradiation, stereotactic body radiation, and reirradiation to treat nonsquamous cancer. Results of the consensus voting are presented along with discussion of the most current evidence. This provides updated evidence-based recommendations and guidelines for the retreatment of recurrent or second primary cancer of the head and neck.

Original languageEnglish
Pages (from-to)759-786
Number of pages28
JournalInternational Journal of Radiation Oncology Biology Physics
Volume113
Issue number4
DOIs
StatePublished - 15 Jul 2022

Fingerprint

Dive into the research topics of 'Retreatment of Recurrent or Second Primary Head and Neck Cancer After Prior Radiation: Executive Summary of the American Radium Society Appropriate Use Criteria'. Together they form a unique fingerprint.

Cite this