(Current Biology 16, 2466–2472; December 19, 2006) Current Biology is retracting this paper, which reports that p53-mediated induction of RhoE in response to genotoxic stress promotes cell survival in part via inhibition of ROCK I-mediated apoptosis. Several years after publication of this work, two corrections to this paper were published in this journal in response to reader concerns regarding apparent duplication of western blots and irregularity of FACS plots in Figures 2 and 4 (https://doi.org/10.1016/j.cub.2012.11.007; https://doi.org/10.1016/j.cub.2016.07.072). A review conducted by Harvard Medical School and Massachusetts General Hospital has now identified further issues involving data within Figure 2. In light of the cumulative issues, we have concluded that the most responsible course of action is therefore to retract the paper. The corresponding author, Sam W. Lee, does not agree with Current Biology's decision to retract the paper.
|Number of pages||1|
|State||Published - 17 Jun 2019|