Retinal blood flow indices in patients infected with human immunodeficiency virus

Chi Wah Yung; Alon Harris; Stephen Massicotte; George Chioran; Gabriel Krombach; Ronald Danis; Sebastian Wolf

doi:10.1136/bjo.80.8.723

Retinal blood flow indices in patients infected with human immunodeficiency virus

Chi Wah Yung, Alon Harris, Stephen Massicotte, George Chioran, Gabriel Krombach, Ronald Danis, Sebastian Wolf

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

Aims/background - Abnormal blood flow dynamics are believed to contribute to the development of retinal microvascular disease in patients infected with human immunodeficiency virus (HIV). In this study, the scanning laser ophthalmoscope (SLO) was used, combined with fluorescein angiography, to measure retinal blood flow indices in HIV seropositive patients. Methods - Arteriovenous passage time (AVP) and perifoveal capillary blood flow velocity (CFV) were measured in 23 HIV infected patients and 23 control subjects with SLO fluorescein angiography. Results - No significant difference in AVP was found between the two groups. However, CFV was significantly reduced in HIV infected patients (p = 0.013). Conclusion - Patients infected with HIV show abnormal haemodynamics at the level of the perifoveal capillaries.

Original language	English
Pages (from-to)	723-727
Number of pages	5
Journal	British Journal of Ophthalmology
Volume	80
Issue number	8
DOIs	https://doi.org/10.1136/bjo.80.8.723
State	Published - Aug 1996
Externally published	Yes

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title = "Retinal blood flow indices in patients infected with human immunodeficiency virus",

abstract = "Aims/background - Abnormal blood flow dynamics are believed to contribute to the development of retinal microvascular disease in patients infected with human immunodeficiency virus (HIV). In this study, the scanning laser ophthalmoscope (SLO) was used, combined with fluorescein angiography, to measure retinal blood flow indices in HIV seropositive patients. Methods - Arteriovenous passage time (AVP) and perifoveal capillary blood flow velocity (CFV) were measured in 23 HIV infected patients and 23 control subjects with SLO fluorescein angiography. Results - No significant difference in AVP was found between the two groups. However, CFV was significantly reduced in HIV infected patients (p = 0.013). Conclusion - Patients infected with HIV show abnormal haemodynamics at the level of the perifoveal capillaries.",

author = "Yung, {Chi Wah} and Alon Harris and Stephen Massicotte and George Chioran and Gabriel Krombach and Ronald Danis and Sebastian Wolf",

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T1 - Retinal blood flow indices in patients infected with human immunodeficiency virus

AU - Yung, Chi Wah

AU - Harris, Alon

AU - Massicotte, Stephen

AU - Chioran, George

AU - Krombach, Gabriel

AU - Danis, Ronald

AU - Wolf, Sebastian

PY - 1996/8

Y1 - 1996/8

N2 - Aims/background - Abnormal blood flow dynamics are believed to contribute to the development of retinal microvascular disease in patients infected with human immunodeficiency virus (HIV). In this study, the scanning laser ophthalmoscope (SLO) was used, combined with fluorescein angiography, to measure retinal blood flow indices in HIV seropositive patients. Methods - Arteriovenous passage time (AVP) and perifoveal capillary blood flow velocity (CFV) were measured in 23 HIV infected patients and 23 control subjects with SLO fluorescein angiography. Results - No significant difference in AVP was found between the two groups. However, CFV was significantly reduced in HIV infected patients (p = 0.013). Conclusion - Patients infected with HIV show abnormal haemodynamics at the level of the perifoveal capillaries.

AB - Aims/background - Abnormal blood flow dynamics are believed to contribute to the development of retinal microvascular disease in patients infected with human immunodeficiency virus (HIV). In this study, the scanning laser ophthalmoscope (SLO) was used, combined with fluorescein angiography, to measure retinal blood flow indices in HIV seropositive patients. Methods - Arteriovenous passage time (AVP) and perifoveal capillary blood flow velocity (CFV) were measured in 23 HIV infected patients and 23 control subjects with SLO fluorescein angiography. Results - No significant difference in AVP was found between the two groups. However, CFV was significantly reduced in HIV infected patients (p = 0.013). Conclusion - Patients infected with HIV show abnormal haemodynamics at the level of the perifoveal capillaries.

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Retinal blood flow indices in patients infected with human immunodeficiency virus

Abstract

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