Results of the Seventh Scientific Workshop of ECCO: Precision Medicine in IBD-Prediction and Prevention of Inflammatory Bowel Disease

Joana Torres, Jonas Halfvarson, Iago Rodríguez-Lago, Charlotte R.H. Hedin, Tine Jess, Marla Dubinsky, Kenneth Croitoru, Jean Frédéric Colombel

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

Inflammatory bowel disease [IBD] is a complex chronic disorder with no clear aetiology and no known cure. Despite recent advances in overall disease management and improved therapeutics, patients with IBD still experience a substantial burden. Furthermore, as the incidence continues to increase in developing areas of the world, it is expected that the burden of IBD to society will increase and exert tremendous pressure on health care systems worldwide. Therefore, new strategies to prevent the global increase of IBD are urgently required. Data are being progressively acquired on the period preceding disease diagnosis, which support the concept that IBD has a preclinical period that may reveal the triggers of disease and may be amenable to early intervention. Having a better knowledge of this preclinical period will increase the potential not only for improved understanding of disease pathogenesis and improved therapeutics, but also for disease prediction and prevention.

Original languageEnglish
Pages (from-to)1443-1454
Number of pages12
JournalJournal of Crohn's and Colitis
Volume15
Issue number9
DOIs
StatePublished - 1 Sep 2021

Keywords

  • Crohn's disease
  • Inflammatory bowel disease
  • biomarkers
  • precision medicine
  • prediction
  • prevention
  • ulcerative colitis

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