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Responsivity to food stimuli in obese and lean binge eaters using functional MRI

  • Allan Geliebter
  • , Talya Ladell
  • , Merranda Logan
  • , Tzipporah Schweider
  • , Mohammad Sharafi
  • , Joy Hirsch

Research output: Contribution to journalArticlepeer-review

106 Scopus citations

Abstract

Functional neuroimaging was employed to study 10 obese and 10 lean healthy young right-handed women, divided equally into binge and non-binge eaters. Subjects were presented with visual and auditory stimuli of binge type foods, non-binge type foods, and non-food stimuli in the fMRI scanner. Brain areas activated by both the visual and auditory stimuli across all individual subjects within a particular group was observed only for the binge food stimuli in the obese binge eaters, in the right premotor area, involved in planning of motor behavior. For four of the five obese binge eaters, the activation was in the ventral premotor cortex adjacent to the oral region, and may reflect past or concurrent motor planning about eating binge foods. Because a random effects group analysis has not yet been completed, this should be considered a preliminary report.

Original languageEnglish
Pages (from-to)31-35
Number of pages5
JournalAppetite
Volume46
Issue number1
DOIs
StatePublished - Jan 2006
Externally publishedYes

Keywords

  • Binge eating disorder
  • Brain imaging
  • Magnetic resonance imaging
  • Obesity
  • Psychological scales

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