@article{eadc35931704469fa77e1bc5bf928b4a,
title = "Response to comments on “Aberrant type 1 immunity drives susceptibility to mucosal fungal infections”",
abstract = "Puel and Casanova and Kisand et al. challenge our conclusions that interferonopathy and not IL-17/IL-22 autoantibodies promote candidiasis in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy. We acknowledge that conclusive evidence for causation is difficult to obtain in complex human diseases. However, our studies clearly document interferonopathy driving mucosal candidiasis with intact IL-17/IL-22 responses in Aire-deficient mice, with strong corroborative evidence in patients.",
author = "{Genomics and Computational Biology Core} and Break, {Timothy J.} and Vasileios Oikonomou and Nicolas Dutzan and Desai, {Jigar V.} and Marc Swidergall and Tilo Freiwald and Daniel Chauss and Harrison, {Oliver J.} and Julie Alejo and Williams, {Drake W.} and Stefania Pittaluga and Lee, {Chyi Chia R.} and Nicolas Bouladoux and Muthulekha Swamydas and Hoffman, {Kevin W.} and Teresa Greenwell-Wild and Bruno, {Vincent M.} and Rosen, {Lindsey B.} and Wint Lwin and Andy Renteria and Pontejo, {Sergio M.} and Shannon, {John P.} and Myles, {Ian A.} and Peter Olbrich and Ferr{\'e}, {Elise M.N.} and Monica Schmitt and Daniel Martin and Barber, {Daniel L.} and Solis, {Norma V.} and Notarangelo, {Luigi D.} and Serreze, {David V.} and Mitsuru Matsumoto and Hickman, {Heather D.} and Murphy, {Philip M.} and Anderson, {Mark S.} and Lim, {Jean K.} and Holland, {Steven M.} and Filler, {Scott G.} and Behdad Afzali and Yasmine Belkaid and Moutsopoulos, {Niki M.} and Lionakis, {Michail S.}",
note = "Funding Information: Supported by the Division of Intramural Research of the NIAID, NIDCR, NCI, NIDDK, and NIDCD, and by NIH grants R01DE022600, R01AI124566 (S.G.F.), and R00DE026856 (M.S.). Publisher Copyright: {\textcopyright} 2021 American Association for the Advancement of Science. All rights reserved.",
year = "2021",
month = sep,
day = "17",
doi = "10.1126/science.abi8835",
language = "English",
volume = "373",
journal = "Science",
issn = "0036-8075",
publisher = "American Association for the Advancement of Science",
number = "6561",
}