TY - JOUR
T1 - Response of rat superior salivatory units to chorda tympani stimulation
AU - Eisenman, J. S.
N1 - Funding Information:
This research was supported by grant BNS 79-07245 from The National Science Foundation. The technical assistance of J. Frey and P. Gannon is gratefully acknowledged.
PY - 1983/6
Y1 - 1983/6
N2 - Unit responses to chorda tympani stimulation in urethane anesthetized rats were characterized by response latency and frequency following ability. One hundred and fifty one units responded with constant latencies, mean: 16.9 msec, S.D.: 7.8 msec. Responses recorded from within the superior salivatory nucleus (SSN) had significantly longer latencies (18.8 ± 6.8, n = 94) than those from surrounding areas (13.5 ± 8.3, n = 50) (p < 0.001). This difference was due to the higher incidence of responses with latencies between 2.7 and 10 msec outside of the SSN (44%) compared to SSN responses (8%). Ability to follow high frequency stimulation ranged from 2-550 Hz, and was the same for SSN neurons and those outside the nucleus. The population of responses localized to the SSN, with latencies greater than 10 msec and with high (> 100 Hz) frequency following, had a mean latency of 20.5 msec. The estimated conduction velocity for these presumed preganglionic, parasympathetic neurons is 0.85 M/sec ± 0.25, significantly slower than that reported for similar responses in cats. The antidromic nature of these responses requires confirmation.
AB - Unit responses to chorda tympani stimulation in urethane anesthetized rats were characterized by response latency and frequency following ability. One hundred and fifty one units responded with constant latencies, mean: 16.9 msec, S.D.: 7.8 msec. Responses recorded from within the superior salivatory nucleus (SSN) had significantly longer latencies (18.8 ± 6.8, n = 94) than those from surrounding areas (13.5 ± 8.3, n = 50) (p < 0.001). This difference was due to the higher incidence of responses with latencies between 2.7 and 10 msec outside of the SSN (44%) compared to SSN responses (8%). Ability to follow high frequency stimulation ranged from 2-550 Hz, and was the same for SSN neurons and those outside the nucleus. The population of responses localized to the SSN, with latencies greater than 10 msec and with high (> 100 Hz) frequency following, had a mean latency of 20.5 msec. The estimated conduction velocity for these presumed preganglionic, parasympathetic neurons is 0.85 M/sec ± 0.25, significantly slower than that reported for similar responses in cats. The antidromic nature of these responses requires confirmation.
KW - Antidromic activation
KW - Conduction velocity
KW - Parasympathetic system Autonomic nervous system
KW - Salivatory neurons
UR - https://www.scopus.com/pages/publications/0020966128
U2 - 10.1016/0361-9230(83)90213-7
DO - 10.1016/0361-9230(83)90213-7
M3 - Article
C2 - 6311360
AN - SCOPUS:0020966128
SN - 0361-9230
VL - 10
SP - 811
EP - 815
JO - Brain Research Bulletin
JF - Brain Research Bulletin
IS - 6
ER -